Evaluation of Outcome in Thymectomized Myasthenia Gravis Patient

Myasthenia gravis is an autoimmune disease characterized by a fluctuating weakness of voluntary muscles (Busch et al. 1996). The weakness of myasthenic patients is due to an antibody-mediated autoimmune attack against acetylcholine receptor at neuromuscular junction (Urschel et al. 1998). Normally impulses travel down the nerve and nerve endings release a substance called acetylcholine. Acetylcholine binds or attaches to receptor on the muscle and makes the muscle contract. The strength of the contraction depends on how much acetylcholine the muscles receive. In myasthenia gravis, Immune system produces antibodies that block or destroy many of the receptor sites for acetylcholine in muscle. Because there are fewer receptor sites, the muscles get fewer nerve signals and become weak. In another form of MG, Immune system produces antibodies to the muscle specific tyrosine kinase protein.

About the author

Dr Mohammad Ata Ullah from a reputed muslim family of Noakhali, Bangladesh. Working at now BSMMU, Dhaka. Interested in research.

Product details

• Authors: Mohamma Ata Ullah, Mohammad Ata Ullah, Asi Baran Adhikary, Asit Baran Adhikary, Md Hoque, Md Rezwanul Hoque
• Publisher: LAP Lambert Academic Publishing
• Languages: English
• Product format: Paperback / Softback
• Released: 11.07.2018
• EAN: 9786139851249
• ISBN: 9786139851249
• No. of pages: 108
• Dimensions: 150 mm x 220 mm x 6 mm
• Weight: 180 g
• Subject: Natural sciences, medicine, IT, technology > Medicine > Medical professions