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This book emphasizes the clinical epidemiology of chronic liver diseases with a specific focus on the methodology of the discussed studies. The whole spectrum of liver diseases is covered, from chronic hepatitis B and C, to hepatocellular carcinoma, alcoholic and non-alcoholic fatty liver diseases and autoimmune and cholestatic liver diseases.
Readers will find the most up-to-date information on clinical epidemiology of hepatology, and will also be able to learn about important methodology and biostatistics information. Each chapter contains a summary table at the end of each chapter that highlights the most relevant landmark studies, their main outcomes and the unique features of the methodology.
The book will appeal to both practicing clinicians as well as clinical research investigators. In addition, this would likely be of interest to medical school or public health school students to learn about hepatology epidemiology, but also some specific fundamentals of clinical research and clinical epidemiology.
List of contents
Introduction.- Principles of Clinical Epidemiology.- Understanding Study Design for Clinical Epidemiology Studies.- Understanding the Interpretation of Disease Incidence and Prevalence.- Understanding Survival Analyses.- Epidemiology of Liver Disease - Worldwide Perspective.- Epidemiology of Liver Disease in the U.S.- Alcoholic Liver Disease.- Hepatitis B Virus - The Asian Perspective.- Hepatitis B Virus - The African Perspective.- Hepatitis B Virus - Western Perspective.- Hepatitis D Virus.- Hepatitis C Virus.- Hepatitis A and Hepatitis E Virus.- Nonalcoholic Fatty Liver Disease.- Hepatocellular Carcinoma.- Autoimmune Liver Diseases and Cholestatic Liver Diseases.- Genetic and Inherited Liver Diseases.- Cryptogenic Liver Diseases and other.- Summary.
About the author
Robert Wong is a graduate of the University of California San Francisco School of Medicine. He completed his internship and residency in internal medicine at California Pacific Medical Center. Following residency, he completed his gastroenterology and hepatology fellowship at Stanford University Hospitals and Clinics during which time he also completed his Masters in Clinical Epidemiology. After completing fellowship, he joined the gastroenterology faculty at Alameda Health System - Highland Hospital, where he also holds an appointment as Assistant Clinical Professor of Medicine at University of California San Francisco School of Medicine. His clinical interests include viral hepatitis and chronic liver diseases. His research interests include clinical epidemiology and outcomes research with a focus on chronic liver diseases and gastrointestinal malignancies.
Dr Gish has made key contributions to hepatitis research and treatment; he was a major early contributor to the decipherment of methods for the detection of hepatitis B and C virus and characterizing its epidemiology and clinical presentation in humans. He was involved in studies that led to the genotypic classification strategies and methods now in use worldwide. As of Sept 26th, Dr Gish has joined, part-time, Dr Richard Manch in Phoenix Arizona at St Joseph’s Hospital and Medical Center to help start a liver transplant program at that facility and to help expand their Liver Disease Center to enhance research and education. In April 2014, Dr Gish joined Stanford to assist with the liver program development as a Professor Consultant.
Summary
1. Summary table with each chapter to highlight key articles and key outcomes from included studies
2. Emphasis on understanding clinical epidemiology, including recent incidence, prevalence, and improved survival trends. Focus will not be on diagnostic approach or treatment approaches
3. Emphasis on the methodology of clinical research studies included with chapters specifically devoted to clinical epidemiology
