Essentials of Antimicrobial Pharmacology - A Guide to Fundamentals for Practice

Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice. For many medical students and physicians, the task of quickly obtaining sufficient, accurate, and up-to-date information about the pharmacology of antimicrobials often involves consulting either lengthy textbooks or inadequate tabular guides. In Essentials of Antimicrobial Pharmacology: A Guide to Fundamentals for Practice, Dr. Axelsen superbly addresses this problem by concisely summarizing the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrating their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. Background discussions explain the fundamentals of measuring antibiotic effect, administering antibiotics, distribution and elimination, sensitivity testing, and dose-response relationships.
Essentials of Antimicrobial Pharmacology: A Guide to Fundamentals for Practice provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

List of contents

1 Introduction.- 1.1. Measures of Antibiotic Effect.- 1.2. Antibiotic Administration.- 1.3. Distribution and Elimination.- 1.4. Sensitivity Testing.- 1.5. Dose-Response Relationships.- 1.6. Resistance.- 2 Antibacterial Agents.- 2.1. Cell Wall Active Agents.- 2.2. Antifolate Agents.- 2.3. Aminoglycosides/Aminocyclitols.- 2.4. Antiribosomal Agents.- 2.5. Topoisomerase Inhibitors.- 2.6. Miscellaneous Agents.- 2.7. Antimycobacterial Agents.- 2.8. Investigational Agents.- 2.9. Combination Antibacterial Therapy.- 2.10. Choosing and Planning Antimicrobial Therapy.- 3 Antifungal Agents.- 3.1. Amphotericin.- 3.2. Flucytosine.- 3.3. Ergosterol Synthesis Inhibitors: Allylamines.- 3.4. Ergosterol Synthesis Inhibitors: Azoles.- 3.5. Caspofungin.- 3.6. Griseofulvin.- 4 Antiparasitic Agents.- 4.1. Antiprotozoan Agents.- 4.2. Antihelminthic Agents.- 5 Antiviral Agents.- 5.1. Antiherpesvirus Agents.- 5.2. Antiinfluenzavirus Agents.- 5.3. Anti-HIV Agents.- 5.4. Miscellaneous Agents.- 6 Immunomodulators and Immunizing Agents.- 6.1. Immunomodulators.- 6.2. Immunization.

Summary

Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

Additional text

"This is the first book I am aware of that reviews only the antimicrobial agents. In general, a book of this kind is very useful." -Doody's Health Sciences Book Review Journal

"...Dr. Axelsen provides sufficient, accurate, up-to-date information for physicians and allied health professionals as well. The quick review and update of pharmacokinetics, adverse effects, and resistance proved helpful for me, and I believe for our readers as well." - Comprehensive Therapy

Report

"This is the first book I am aware of that reviews only the antimicrobial agents. In general, a book of this kind is very useful." -Doody's Health Sciences Book Review Journal

"...Dr. Axelsen provides sufficient, accurate, up-to-date information for physicians and allied health professionals as well. The quick review and update of pharmacokinetics, adverse effects, and resistance proved helpful for me, and I believe for our readers as well." - Comprehensive Therapy

Product details

• Authors: Paul H Axelsen, Paul H. Axelsen
• Assisted by: Paul H. Axelsen (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 01.12.2011
• EAN: 9780896037601
• ISBN: 978-0-89603-760-1
• No. of pages: 142
• Weight: 329 g
• Illustrations: VIII, 142 p.
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Pharmacy; C, Diseases, Infectious & contagious diseases, Pharmacology, infectious diseases, Biomedical and Life Sciences, Pharmacology/Toxicology