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Filling the gap for an up-to-date reference that presents the field of organophosphorus chemistry in a comprehensive and clearly structured way, this one-stop source covers the chemistry, properties, and applications from life science and medicine. Divided into two parts, the first presents the chemistry of various phosphorus-containing compounds and their synthesis, including ylides, acids, and heterocycles. The second part then goes on to look at applications in life science and bioorganic chemistry. Last but not least, such important practical aspects as 31P-NMR and protecting strategies for these compounds are presented.
For organic, bioinorganic, and medicinal chemists, as well as those working on organometallics, and for materials scientists. The book, a contributed work, features a team of renowned scientists from around the world whose expertise spans the many aspects of modern organophosphorus chemistry.
List of contents
Phosphines and related tervalent phosphorus systems
Recent developments in phosphonium chemistry
Phosphorus ylides and related compounds
Low-coordinate phosphorus compounds with phosphaorganic multiple bond systems
Pentacoordinate phosphorus compounds
Hexacoordinate phosphorus compounds
Methods for the introduction of the phosphonate moiety into complex organic molecules
Phosphorus heterocycles
Modern aspects of 31P NMR spectroscopy
Phosphorus in chemical biology and medicinal chemistry
Future trends in organophosphorus chemistry
About the author
Viktor O. Iaroshenko was born in 1980 in Kiev, Ukraine. He received his MS in chemistry (2003) and PhD in organic chemistry (2009) from Kyiv National Taras Shevchenko University (Ukraine) under the supervision of Prof. Dr. Sci. Andrey A. Tolmachev. 2009-2013 he was a group leader (assistant professor) at the Chemistry Institute, University of Rostock, Germany. 2013-2014 he was a visiting research assistant professor at University of Illinois at Chicago, Chicago, USA. Presently he is a Principle Investigator and a head of Laboratory of Homogeneous Catalysis and Molecular Design at Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Poland. His scientific interests include drug discovery, application of fluorine and phosphorus chemistry in molecular and drug design, combinatorial chemistry, chemistry of heterocyclic compounds, element organic chemistry and green chemistry. He is co-author of more than 75 papers. He is also recipient of several grants from Polish National Science Centre (NCN).
Summary
Filling the gap for an up-to-date reference that presents the field of organophosphorus chemistry in a comprehensive and clearly structured way, this one-stop source covers the chemistry, properties, and applications from life science and medicine. Divided into two parts, the first presents the chemistry of various phosphorus-containing compounds and their synthesis, including ylides, acids, and heterocycles. The second part then goes on to look at applications in life science and bioorganic chemistry. Last but not least, such important practical aspects as 31P-NMR and protecting strategies for these compounds are presented.
For organic, bioinorganic, and medicinal chemists, as well as those working on organometallics, and for materials scientists. The book, a contributed work, features a team of renowned scientists from around the world whose expertise spans the many aspects of modern organophosphorus chemistry.
