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Part of the highly regarded Diagnostic Pathology series, this updated volume covers all aspects of placental pathology and the critical role the placenta plays in the unique interface between mother and fetus. Concise, focused chapters, supported by tables, diagrams, and photographs, keep you up-to-date with evolving changes in the questions and issues concerning both the fetus/infant and the mother. This revised edition is ideal for pathologists at all levels of experience and training for use as a quick reference and as an efficient review to improve knowledge and skills.
- Covers all areas of placental pathology, with clear and concise information on gross and microscopic changes of the placenta, common diagnoses, and placental evaluation in special circumstances
- Provides expert guidance on key topics, such as maternal mortality, gestational trophoblastic disease, placental pathology constellations, and typical clinical correlates; pregnancy complications, such as preeclampsia, intrauterine growth restriction, and multiple gestation; and the pathology of disorders of placental implantation and the postpartum hysterectomy
- Features detailed, up-to-date information on maternal COVID-19 and placental pathology, including SARS-CoV-2 placentitis, and new chapters on fetal hydrops, common placental associations with stillbirth, second-trimester demise, and more
- Contains significantly updated information throughout, including new content, images, and references to reflect the most current diagnoses and provide ease for daily case sign-out
- Features more than 1,850 print and online images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, radiology images, and online video content (including quick tutorials on key pathologic diagnoses) to help practicing and in-training pathologists reach a confident diagnosis
- Employs consistently templated chapters, bulleted content, key facts, annotated images, reference tables for placental evaluation, sample templates for gross and microscopic placental description, and an extensive index for quick, expert reference at the point of care
- Includes an eBook version that provides you access to all text, figures, and references with the ability to search and customize your content, have it read aloud, and make notes and highlights
List of contents
Overview of Gross and Microscopic Changes
Umbilical Cord
Gross Evaluation and Normal Histology of Umbilical Cord
Knots
Umbilical Cord Edema and Thinning
Histopathologic Changes of Umbilical Cord
Extraplacental Membranes
Gross Evaluation and Normal Histology of Membranes
Histopathologic Changes of Membranes
Chorionic Plate
Gross Evaluation and Normal Histology of Chorionic Plate
Histopathologic Changes of Chorionic Plate
Stem Villi
Gross Evaluation and Normal Histology of Stem Villi
Histopathologic Changes of Stem Villi
Chorionic Villi
Gross Evaluation and Normal Histology of Chorionic Villi
Histopathologic Changes of Chorionic Villi
Septa, Intervillous Space, and Basal Plate
Gross Evaluation and Normal Histology of Septa, Intervillous Space, and Basal Plate
Histopathologic Changes of Septa, Intervillous Space, and Basal Plate
Decidua
Gross Evaluation and Normal Histology of Decidua
Histopathologic Changes of Decidua
Placental Diagnoses
Meconium
Meconium-Stained Placenta
Amniotic Fluid Infection Sequence
Amniotic Fluid Infection Sequence (Maternal and Fetal Inflammatory Response)
Group B Streptococcus
Other Bacterial and Mycobacterial Species
Candida
Placental Infections With Villitis and Other Findings
Cytomegalovirus
Parvovirus B19
Herpes Simplex Virus
Other Viruses
Syphilis
Coccidioidomycosis
Parasites
Chronic Inflammatory Lesions
Cellular Composition of Chronic Inflammatory Lesions
Chronic Villitis and Intervillositis
Basal Chronic Villitis and Chronic Deciduitis
Chronic Chorioamnionitis
Eosinophilic/T-Cell Chorionic Vasculitis
Massive Perivillous Fibrin Deposition and Maternal Floor Infarction
Massive Perivillous Fibrin Deposition and Maternal Floor Infarction
Fetal Vasculopathy
Large Vessel Fetal Vascular Occlusion
Distal Villous Lesions Associated With Fetal Vascular Occlusion
Placental Abruption
Acute Abruption and Retroplacental Hematoma
Chronic Abruption
Villous Hypervascular Lesions
Chorangiosis
Chorangiomatosis
Chorangioma
Gestational Trophoblastic Disease and Metastatic Tumors
Hydropic Degeneration Mole
Partial Hydatidiform Mole
Complete Hydatidiform Mole
Choriocarcinoma
Placental Site Nodule and Exaggerated Placental Site
Placental Site Trophoblastic Tumor and Epithelioid Trophoblastic Tumor
Metastatic Tumors
Placental Mesenchymal Dysplasia
Placental Mesenchymal Dysplasia
Placental Evaluation in Special Circumstances
Gestational Diabetes
Gestational Diabetes
Placentomegaly
Distal Villous Immaturity
Preeclampsia and Uteroplacental Malperfusion
Preeclampsia and Related Hypertensive Disorders
Small for Gestational Age Placenta
Distal Villous Hypoplasia
Maternal Decidual Vasculopathy
Infarcts
Extravillous Cytotrophoblast Cysts
Laminar Decidual Necrosis
Fetal-Maternal Hemorrhage
Fetal-Maternal Hemorrhage
Intrauterine Growth Restriction
Placental Causes of Poor Fetal Growth
Prematurity
Placental Findings in Premature Birth
Abnormal Placental Implantation
Placenta Accreta
Intrauterine Fetal Demise
1st-Trimester Pregnancy Loss
2nd-Trimester Fetal Demise
3rd-Trimester Fetal Demise
Recurrent Pregnancy Loss
In Utero Demise to Delivery Interval Changes
Hypoxic Ischemic Encephalopathy
Multiple Gestations
Complications of Monochorionic Monoamniotic Twin Gestations
Twin
About the author
Amy Hereema-McKenney, MD is a board certified anatomical pathologist who is a subspecialist in placental, perinatal, and pediatric pathology at the Cleveland Clinic, in Cleveland, OH. McKenney is responsible for pathologic evaluation of placentas from deliveries at Cleveland Clinic main campus and regional affiliate hospitals, as well as review of cases sent in for expert consultation.
