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Several small heterocyclic molecules are very important in organic and medicinal chemistry. Their synthetic strategies are significant in drug discovery. And most of them are major constituent of several natural compounds such as alkaloids, histamine, histidine, biotin, nucleic acid etc. Many heterocyclic derivatives are being developed for different therapeutic actions. Interestingly they exhibited biological activities such as antimicrobial, anticancer, analgesic, anti-inflammatory, antiviral, anthelmintic, anticoagulant, anti-ulcer, anti-allergic activity etc. Therefore, this book firstly in three chapters aims to review some important small heterocyclic molecules (Flouroquinoline, Cumarines, Oxzasolidenones, Imidazole) its chemistry, synthesis and pharmacological activities. The subject of this book becomes a significant publication for anyone interested in synthesis and biomedical applications of heterocyclic small molecules. It provides a permanent written record deals with the synthetic approach along with their applications in medicinal chemistry.
About the author
Dr. Mardia T. El Sayed and Dr. Nermien M. Sabry are Egyptian Professors at National Research Center, Chemical Industries Division, Applied Organic Chemistry Department. Prof. Nermien Sabry is currently working in King Khalid University, Saudi Arabia. Dr. Nesrin M. Morsy is a Professor in Department of Organometallic and Organometalloid Chemistry.
