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List of contents
Important Biological Features. Husbandry. Management. Clinical Medicine. Preventive Medicine. Experimental Methodology. Resources and Additional Information. Appendix A: Glossary of Phenotyping Terminology and Tests. Appendix B: Suggested Cassette Numbering System and Some Trimming Suggestions. Index.
About the author
Peggy J. Danneman is a Senior Director of Laboratory Animal Health Services at The Jackson Laboratory in Bar Harbor, Maine. Mark A. Suekow is the Director of the Freimann Life Sciences Center at the University of Notre Dame, Indiana. Cory Brayton is the Director of Phenotyping Core for Johns Hopkins Medicine, Maryland.
Summary
Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse.
Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse.
