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This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.
List of contents
Introduction.- Microfluidic Systems.- Lab-on-a-chip Systems for Cellomics - Materials and Technology.- Organ-on-a-chip Systems.- Biological Bases of Cardiac Function and the Pro-Regenerative Potential of Stem Cells in the Treatment of Myocardial Disorder.- Pluripotent and Mesenchymal Stem Cells - Challenging Sources for Derivation of Myoblast.- Microfluidic Systems for Cardiac Cell Culture - Characterization.- Heart-on-a-chip Systems .- Cardiac Cell Culture Microtechnologies Based on Stem Cells.
About the author
Zbigniew Brzozka is Professor in the Chair of Medical Biotechnology and Head of the Lab-on-a-Chip group at Warsaw University of Technology.
Elzbieta Jastrzebska is Assistant Professor in the Chair of Medical Biotechnology at Warsaw University of Technology.
Summary
This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.
