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This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of "atypical" diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.
List of contents
Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice.- Prostate Needle Biopsy Sampling Techniques: Impact on Pathological Diagnosis.- Diagnosis of Limited Cancer in Prostate Biopsy.- Immunohistochemistry in Prostate Biopsy Evaluation.- Contemporary Approach to Gleason Grading of Prostate Cancer.- Histologic Variants of Prostate Carcinoma.- Benign Mimics of Prostate Carcinoma.- Atypical Cribriform Lesions in Prostate Biopsy: Relationship to Prostate Carcinoma, Differential Diagnosis, and Emerging Concepts of Intraductal Carcinoma of the Prostate.- High-Grade Prostatic Intraepithelial Neoplasia.- Atypical Glands Suspicious for Cancer.- Spindle Cell Lesions of the Prostate Gland.- Treatment Effect in Benign and Malignant Prostate Tissue.- Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers.- Biopsy Specimen Handling, Processing, Quality Assurance Program.- Reporting of Prostate Biopsy.
Summary
This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of “atypical” diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.
Additional text
From the reviews:
“This text is derived from a course that the 2 authors presented at a national meeting over the course of several years. … The emphasis of the text is on problems that may arise in examining prostate biopsies … . The authors have done a wonderful job of bringing their well-received course to the printed page. … This text is likely to find a place on the shelves of many pathologists who interpret prostate needle biopsies.” (Andrew Renshaw, Advances in Anatomic Pathology, Vol. 20 (2), March, 2013)
Report
From the reviews:
"This text is derived from a course that the 2 authors presented at a national meeting over the course of several years. ... The emphasis of the text is on problems that may arise in examining prostate biopsies ... . The authors have done a wonderful job of bringing their well-received course to the printed page. ... This text is likely to find a place on the shelves of many pathologists who interpret prostate needle biopsies." (Andrew Renshaw, Advances in Anatomic Pathology, Vol. 20 (2), March, 2013)
