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Glioma Signaling is a text reference on cellular signaling processes focused on the mechanism of nucleotide receptors activation by exogenic nucleotides and the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration changes, cellular growth, progression and invasion, as well as presents perspective concerning potential targets for glioma therapy.
List of contents
1.introduction to purinergic signaling in the brain. - 2. adenosine signaling in glioma cells. - 3. cross-talk in nucleotide signaling in glioma c6 cells. - 4. calcium signaling in glioma cells - the role of nucleotide receptors. - 5. purinergic signaling in glioma progression. - 6. cytoskeleton and nucleotide signaling in glioma cells. - 7. signaling determinants of glioma cell invasion. - 8. receptor tyrosine kinases: principles and functions in glioma invasion. - 9. tgf beta signaling and its role in glioma pathogenesis. - 10. stat signaling in glioma cells. - 11. cannabinoid signaling in glioma cells.
Summary
Glioma Signaling is a text reference on cellular signaling processes focused on the mechanism of nucleotide receptors activation by exogenic nucleotides and the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration changes, cellular growth, progression and invasion, as well as presents perspective concerning potential targets for glioma therapy.
Additional text
From the book reviews:
“This is the single best current reference on signal transduction mechanisms in gliomas … . The book is geared for biochemists, neurophysiologists, neurosurgeons, neurologists, students, and research fellows working on brain tumors from the point of view on diagnosis, pathophysiology, invasion, metastases, and potential molecular therapies of promise.” (Joseph J. Grenier, Amazon.com, July, 2014)
Report
From the book reviews:
"This is the single best current reference on signal transduction mechanisms in gliomas ... . The book is geared for biochemists, neurophysiologists, neurosurgeons, neurologists, students, and research fellows working on brain tumors from the point of view on diagnosis, pathophysiology, invasion, metastases, and potential molecular therapies of promise." (Joseph J. Grenier, Amazon.com, July, 2014)
