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Atherosclerosis represents the leading cause of mortality and morbidity in the world. Two of the most common, severe, diseases that may occur, acute myocardial infarction and stroke, have their pathogenesis in the atherosclerosis that may affect the coronary arteries as well as the carotid/intra-cranial vessels. Therefore, in the past there was an extensive research in identifying pre-clinical atherosclerotic diseases in order to plan the correct therapeutical approach before the pathological events occur. In the last 20 years imaging techniques and in particular Computed Tomography and Magnetic Resonance had a tremendous improvement in their potential. In the field of the Computed Tomography the introduction of the multi-detector-row technology and more recently the use of dual energy and multi-spectral imaging provides an exquisite level of anatomic detail. The MR thanks to the use of strength magnetic field and extremely advanced sequences can image human vessels very quickly while offering an outstanding contrast resolution.
List of contents
1 Principles of Computed Tomography.-2 CT Imaging of Coronary Arteries.-3 CT of carotid arteries.-4 CT imaging of intracranial vessels.-5 Intravenous flat panel detector CT angiography for the assessment of intracranial arteries .-6 Basic Principles of Magnetic Resonance Imaging .-7 MR imaging of vulnerable carotid atherosclerotic plaques.-8 Cardiovascular magnetic resonance imaging of coronary arteries.-9 MRI of intracranial atherosclerosis.-10 Evolving technologies in MR and PET for imaging atherosclerosis.
About the author
Dr. Luca Saba received his MD from the University of Cagliari, Italy. Today he works in the Azienda Ospedaliero Universitaria of Cagliari. Dr Saba's research fields focus on Multi-Detector-Row Computed Tomography, Magnetic Resonance, Ultrasound, Neuroradiology, and Diagnostic in Vascular Sciences. He is a member of the Italian Society of Radiology (SIRM), Eurpoean Society of Radiology (ESR), Radiological Society of North America (RSNA), American Roentgen Ray Society (ARRS) and European Society of Neuroradiology (ESNR).
Dr. Rikin A Trivedi LLB (Hons.) MRCP(UK) FHEA(UK) FRCS(SN) PhD, is a cerebrovascular surgeon, scientist, trainer and educator in the fields of neurosurgery, medicine and neuroimaging.
Dr. Jasjit S. Suri, PhD, MBA, Fellow AIMBE, received his MS in Neurological MRI from the University of Illinois, Chicago, USA; his PhD in Cardiac Imaging from University of Washington, Seattle, Washington, USA; and his MBA from Ivy League Weatherhead School of Management, Case Western Reserve University, Cleveland, USA.
Summary
Atherosclerosis represents the leading cause of mortality and morbidity in the world. Two of the most common, severe, diseases that may occur, acute myocardial infarction and stroke, have their pathogenesis in the atherosclerosis that may affect the coronary arteries as well as the carotid/intra-cranial vessels. Therefore, in the past there was an extensive research in identifying pre-clinical atherosclerotic diseases in order to plan the correct therapeutical approach before the pathological events occur. In the last 20 years imaging techniques and in particular Computed Tomography and Magnetic Resonance had a tremendous improvement in their potential. In the field of the Computed Tomography the introduction of the multi-detector-row technology and more recently the use of dual energy and multi-spectral imaging provides an exquisite level of anatomic detail. The MR thanks to the use of strength magnetic field and extremely advanced sequences can image human vessels very quickly while offering an outstanding contrast resolution.
