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Having been a fairly dormant specialty for many decades, in recent years there has been a remarkable increase in activity in Neuro-oncology from basic science through to the clinics. Reflecting this there have been considerable advancements in the understanding of the biology of CNS malignancies which have infirmed the development of many novel and successful therapies. This work aims to bring together the scattered literature on the new concepts in neuro-oncology for the benefit of those in the field. The book moves from concepts in the scientific basis of neuro-oncology, through to modelling techniques and finishing on the translation into clinical practice.
List of contents
1. Classification of Gliomas.- 2. Epigenetics and Brain Cancer.- 3. Astrocyte Differentiation from Oligodendrocyte Precursors.- 4. Stem Cells and Brain Cancer.- 5. In Vitro Models of Brain Cancer.- 6. Mouse Models of Glioma Pathogenesis: History and State of the Art.- 7. The Application of Novel Ionising Radiation Species for Glioblastoma.- 8. Advances in Imaging Brain Cancer.- 9. Surgical Management of Glial Cancers.- 10. Radiation Oncology in Brain Cancer.- 11. Managing the Elderly Patient.- 12. Brain Tumour Presentation in Children and Young People.- 13. How Can We Improve Clinical Trial Recruitment in Neuro-Oncology?
About the author
Colin Watts is a Clinician Scientist and Honorary Consultant Neurosurgeon at the Department of Clinical Neurosciences, Cambridge Centre for Brain Repair and Neurosurgery Unit, Cambridge University.
Summary
Having been a fairly dormant specialty for many decades, in recent years there has been a remarkable increase in activity in Neuro-oncology from basic science through to the clinics. The book moves from concepts in the scientific basis of neuro-oncology, through to modelling techniques and finishing on the translation into clinical practice.
Additional text
From the book reviews:
“This is an up to date reference on the surgical, chemotherapy, and radiosurgery of gliomas, both low and high grade neoplasms. … I highly recommend this book for neurosurgeons, oncologists, radiation researchers, fellows and students.” (Joseph J. Grenier, Amazon.com, October, 2014)
“In this book, the authors aim to comprehensibly describe new findings, as well as established facts, and to discuss their influence on current and possible future therapies. … this is a well written book on current advances in the field of neuro-oncology. It is worth reading for basic researchers working in the field of neuro-oncology, as well as neuro-oncologists and neurosurgeons.” (Anne-Katrin Hickmann, Innovative Neurosurgery, Vol. 1 (1), 2013)
Report
From the book reviews:
"This is an up to date reference on the surgical, chemotherapy, and radiosurgery of gliomas, both low and high grade neoplasms. ... I highly recommend this book for neurosurgeons, oncologists, radiation researchers, fellows and students." (Joseph J. Grenier, Amazon.com, October, 2014)
"In this book, the authors aim to comprehensibly describe new findings, as well as established facts, and to discuss their influence on current and possible future therapies. ... this is a well written book on current advances in the field of neuro-oncology. It is worth reading for basic researchers working in the field of neuro-oncology, as well as neuro-oncologists and neurosurgeons." (Anne-Katrin Hickmann, Innovative Neurosurgery, Vol. 1 (1), 2013)