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This book provides the latest information about hairy root culture and its several applications, with special emphasis on potential of hairy roots for the production of bioactive compounds. Due to high growth rate as well as biochemical and genetic stability, it is possible to study the metabolic pathways related to production of bioactive compounds using hairy root culture. Chapters discuss the feasibility of hairy roots for plant derived natural compounds. Advantages and difficulties of hairy roots for up-scaling studies in bioreactors are included as well as successful examples of hairy root culture of plant species producing bioactive compounds used in food, flavors and pharmaceutical industry. This book is a valuable resource for researchers and students working on the area of plant natural products, phytochemistry, plant tissue culture, medicines, and drug discovery.
List of contents
The Agrobacterium rhizogenes GALLS Gene Provides an Alternative Method to Transform Plants.- Hairy Root Composite Plant Systems in Root-Microbe Interaction Research.- Production and Biosynthesis of Bioactive Stilbenoids in Hairy Root Cultures.- Hairy Root Cultures of Rhodiola rosea to Increase Valuable Bioactive Compounds.- Production of Indole Alkalids in Catharanthus roseus L. Hairy Root Cultures.- Enhancement of Medicinally Important Bioactive Compounds in Hairy Root Cultures of Glycyrrhiza, Rauwolfia and Solanum through In Vitro Stress Application.- An Efficient Hairy Root System for Withanolide Production in Withania somnifera (L.) Dunal.- Hairy Root Culture of Nicotiana Tabacum (Tobacco) as a Platform for Gene Manipulation of Secondary Metabolism.- Synthesis of Benzylisoquinoline Alkaloids and Other Tyrosine Derived Metabolites in Hairy Root Cultures.- Mass Production of Transformed Hairy Root for Secondary Metabolites. - ACase Study of Panax ginseng Hairy Roots.- Production of Ginsenosides by Hairy Root Cultures of Panax ginseng.
About the author
Dr. Malik has obtained her doctoral degree in Plant Biotechnology from CSIR- Institute of Himalayan Bioresource Technology, Palampur, India in July 2009. She did Masters (Gold Medalist) in Honours Botany with specialization in Plant Biotechnology and Tissue Culture in 2001 from Guru Nanak Dev University, Amritsar, India. Her basic area of research is plant secondary metabolites and genetic manipulation and she did work on several medicinal plants. After her post-doctoral studies at Brazil, Czech Republic and United Kingdom, Dr. Malik has joined as a Professor in Biology at Biological and Health Sciences Center, Federal University of Maranhão, Sao Luis since February 2014. At present she is an active member of Post-graduate research program at UFMA and actively involved in research, teaching and supervising research students at UG/PG levels. She has been awarded as FAPEMA Junior Researcher grant in August 2015. To date, Dr. Malik has published more than 20 research articles in reputed journals, 6 book chapters and several abstracts in National and International conferences/symposia. She is editorial board member and reviewer of many International Scientific Journals.
Summary
This book provides the latest information about hairy root culture and its several applications, with special emphasis on potential of hairy roots for the production of bioactive compounds. Due to high growth rate as well as biochemical and genetic stability, it is possible to study the metabolic pathways related to production of bioactive compounds using hairy root culture. Chapters discuss the feasibility of hairy roots for plant derived natural compounds. Advantages and difficulties of hairy roots for up-scaling studies in bioreactors are included as well as successful examples of hairy root culture of plant species producing bioactive compounds used in food, flavors and pharmaceutical industry. This book is a valuable resource for researchers and students working on the area of plant natural products, phytochemistry, plant tissue culture, medicines, and drug discovery.
