G Protein-coupled Receptors - Emerging Paradigms in Activation, Signaling and Regulation

Informationen zum Autor Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

List of contents

1. Classical Paradigms of GCPR signaling and regulation
2. The family of small GTPases: Beyond heterotrimeric G proteins
3. GPCR endocytosis: Arrestins, arrestin-like proteins and beyond
4. Signaling from internalized G Protein-Coupled Receptors
5. GPCR kinases: Something old, something new
6. Ubiquitination of GPCRs: Roles in endocytosis and receptor turnover
7. RAMPs: Discovery and future perspective
8. Cross-talk between GPCRs and RTKs: Novel signaling platforms
9. "Regulator of G protein signaling" protein family: Fine-tuning and emerging paradigms
10. GCPR-interacting lipids: Structural, functional and signaling implications

Product details

• Authors: Arun K. Shukla, Arun K. (EDT) Shukla
• Assisted by: Arun K. Shukla (Editor)
• Publisher: Academic Press London
• Languages: English
• Product format: Hardback
• Released: 31.05.2018
• EAN: 9780128137727
• ISBN: 978-0-12-813772-7
• No. of pages: 182
• Series: International Review of Cell a; International Review of Cell and Molecular Biology
• Subjects: Natural sciences, medicine, IT, technology > Biology > General, dictionaries; SCIENCE / Life Sciences / Molecular Biology, SCIENCE / Life Sciences / Cell Biology, molecular biology, Cellular biology (cytology), Developmental biology