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Informationen zum Autor Dr Helena S. Azevedo is a senior Lecturer in Biomedical Engineering and Biomaterials at Queen Mary University of London, UK. She has more than 15 years of research experience in biomaterials engineering and has developed significant work on the development of self-assembling biomaterials for biomedical applications. Dr. Ricardo da Silva has 13 years of research experience in the field of Biomaterials for Regenerative Medicine applications. His research work covers thermo-responsive polymers for drug delivery and cell sheet engineering, peptide self-assembly and supramolecular chemistry. He is a Research fellow at King’s College London, at the Centre for Craniofacial and Regenerative Biology, where he develops his research activities in self-assembling biomaterials and bone tissue engineering.
List of contents
1. Self-assembling biomaterials: beginnings and progress over the past decade
Part 1 Molecular building blocks for self-assembly
2. Designing peptides for self-assembling biomaterials with controlled mechanical and biological performance
3. Engineering silk fibroin for hydrogel self-assembly
4. Elastin-like proteins - modular design for self-assembly
5. Sweet building blocks for self-assembling biomaterials with molecular recognition
6. Peptoid self-assembly and opportunities for biomaterials and biointerfaces
7. Lipid bolaamphiphiles for fabricating membrane-mimetic biomaterials
8. Self-assembling protein-DNA hybrid molecules as building blocks for complex biomaterials
9. Biomaterials based on ureido-pyrimidinone (UPy) and benzene-1,3,5-tricarboxamide (BTAs) supramolecular polymers
10. Self-assembling of biomaterials using host-guest chemistry
Part 2 Unique properties of self-assembling biomaterials: blurring the frontiers between biomaterials and biology
11. Adaptive supramolecular biomaterials through non-equilibrium self-assembly
Part 3 Nanoscale characterization of self-assembling biomaterials
12. Unveiling complex structure and dynamics in supramolecular biomaterials using super-resolution microscopy
13. Probing local molecular dynamics in self-assembling systems with electron paramagnetic resonance (EPR) spectroscopy
14. Small angle X-ray scattering (SAXS) to study spatial arrangement in self-assembled biomaterials
15. Studying nanoscale interactions in self-assembling systems through molecular simulations
Part 4 Mechanisms of self-assembly: controlling driving forces and boundaries for self-assembly across scales
16. Magnetic fields to align peptide assemblies and provide directionality in biomaterials
17. Using confined environments to control the shape and size of assemblies
18. Engineering dynamic self-assembling biomaterials at the interface
19. Enzymatic mediated self-assembly
Part 5 Applications of self-assembling biomaterials
20. Recreating stem cell niches using self-assembling biomaterials
21. Bioactive self-assembling scaffolds for regenerative medicine
22. Functionalization of self-assembling peptides for neural tissue engineering
23. Self-assembling biomaterials as nanocarriers for the targeted delivery of drugs for cancer
24. Self-assembling biomaterials for theranostic applications
25. Self-assembling artificial enzymes: biomaterial therapies for metabolic diseases
