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Herbal medicines have been widely used all over the world since ancient times and have been recognized by physicians and patients for their better therapeutic value as they have fewer adverse effects as compared with modern medicines. Novel drug delivery systems not only reduce the repeated administration to overcome non-compliance, but also help to increase the therapeutic value by reducing toxicity and increasing the bioavailability, and so on. For a long time herbal medicines were not considered for development as novel formulations owing to lack of scientific justification and processing difficulties, such as standardization, extraction and identification of individual drug components in complex polyherbal systems. However, modern phytopharmaceutical research solves the scientific needs for herbal medicines as in modern medicine, which gives way for developing novel formulations such as nanoparticle, micro emulsions, matrix systems, solid dispersions, liposomes, solid lipid nanoparticle, and so on. An extensive research is going on in the area of novel drug delivery and targeting for plant actives and extracts. However, research in this area is still at the exploratory stage.
About the author
Dr. Kapil Kumar ist Assistenzprofessor an der School of Pharmacy and Technology Management, SVKM's NMIMS, Hyderabad, Indien. Sein Forschungsinteresse gilt der Synthese neuer chemischer Substanzen mit pharmakologischer Wirkung. Er ist aktiv an der Entdeckung und Entwicklung von Arzneimitteln beteiligt.
Summary
The funny thing about stop signs is that they're also start signs.
Mayzie is the middle sister, sent to private school because of her brains. Brooks, the oldest, is a beautiful athlete who's conflicted about her two loves: softball and Dave. Palmer is the youngest, tentative in all but her blistering pitches as the only freshman on varsity softball. Though very different, the Golds are sisters through and through.
When the unthinkable happens -- the death of their father -- a year passes in shattered silence. Brooks begins drinking, Palm withdraws, and May is left to fend for herself. She gets a job at a coffee spot, and hits the books. But the one thing she can't do alone is learn to drive. That's when Peter, her lifelong nemesis and all around thorn-in-side, assumes a surprising new role in May's life: he teaches her to drive, and the connection between them changes from childhood animosity to one that May can't understand, or doesn't yet want to.
As May slowly starts to pick up the pieces of her life, her sisters struggle with their own demons. The Gold sisters have been changed irrevocably, and they are all but lost to one another, until the key is found. The key to their father's Pontiac Firebird.
