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The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials.
The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.
List of contents
Cardiac Imaging of Platelets and Inflammation.- Inflammation and Atherosclerosis.- Vaccination to Prevent Cardiovascular Disease.- Platelets as Regulators of Thrombosis and Inflammation.- Diversity of Inflammatory Cells in Vascular Degenerative Disease.- Platelet Inhibition as a Therapeutic Approach in Intravascular Intervention.- Diabetes, Thrombosis, and Cardiovascular Risks.- Therapeutic and Diagnostic Antibody Development.- Diabetes, Inflammation, and Platelets.- Platelet chemokines.- Platelet Signaling.- AMPs and Inflammation.- Platelets and Regeneration.- Platelets HMGB1 and cardiogenic schock.- Platelet cGMP and Vascular motion.- Platelet and Stroke.- Platelets and Polymorphisms.
About the author
Prof. Dr. Andreas Zirlik
University-Heart Center Freiburg-Bad Krozingen
Cardiology and Angiology I
Freiburg, Germany
Prof. Dr. Christoph BodeUniversity-Heart Center Freiburg-Bad KrozingenCardiology and Angiology IFreiburg, Germany
Prof. Dr. Meinrad GawazDeutsches Herzkompetenz Zentrum – University Hospital TübingenCardiologyTübingen, Germany
Summary
The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials.
The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.
Additional text
“A focus of the book is on the link between haemostasis and inflammation, and the roles that platelets play in both. It also aims to describe recent advances in basic science and early results of clinical trials. The book is written for biomedical scientists specializing in vascular biology, biochemistry or immunology. … this textbook is likely to be best value for money for purchase by libraries at academic institutions … .” (Michael J.R. Desborough, British Journal of Hospital Medicine, Vol. 79 (3), March 2018)
Report
"A focus of the book is on the link between haemostasis and inflammation, and the roles that platelets play in both. It also aims to describe recent advances in basic science and early results of clinical trials. The book is written for biomedical scientists specializing in vascular biology, biochemistry or immunology. ... this textbook is likely to be best value for money for purchase by libraries at academic institutions ... ." (Michael J.R. Desborough, British Journal of Hospital Medicine, Vol. 79 (3), March 2018)
