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Reviews the foundations of geriatric neurology, including the fundamentals of age associated changes in molecular biology, altered pharmacokinetics and psychopharmacology that make drug therapy in the elderly different from younger patients Contains major advances in our understanding of neurodegenerative diseases Features contributions from world leaders in geriatric neurology-the broadest, most expert coverage available
List of contents
Section I. Foundations and Principles of Geriatric Neurology1. Geriatric pharmacotherapy: Appraising new drugs for neurological disorders in older patients
2. Animal models of cognitive aging and circuit-specific vulnerability
3. Psychopharmacology and pharmacokinetics
4. Models of care
5. Neurologic examination in the elderly
6. Cognitive and neuropsychological evaluation of the elderly
7. Chronic neurological disorders and related comorbidities: Role of age-associated physiological changes
8. Autonomic dysfunction: diagnosis and management
9. Epidemiology of aging and associated neurological disorders: Prevalence and incidence of Alzheimer disease and other dementias
10. Neuropsychology of aging
11. Cognitive reserve
12. Neuroimaging in aging and neurological diseases
Section II. Neurological Disorders of Late-Life13. Alzheimer disease
14. Parkinson disease - diagnosis and appreciation of comorbidities
15. Frontotemporal dementia
16. Recognizing and treating atypical Parkinson disorders
17. Down syndrome
18. The long-term consequences of repetitive head impacts: Chronic traumatic encephalopathy
19. Delirium in the critically ill patient
20. Vascular cognitive impairment: a preventable component of dementia
21. Stroke in the elderly
22. Gait and dementia
23. Assessment and treatment of major depression in older adults
24. Neuropsychiatric symptoms in dementia
25. Epilepsy and aging
26. Sleep physiology and disorders in aging and dementia
Section III. General Topics in Geriatric Neurology27. Urological function and dysfunction in aging: Diagnosis and treatment
28. Geriatric rehabilitation
29. Palliative medicine and end-of-life care
30. Headache in the elderly
31. Driving in the elderly in health and disease
32. The evolution of geriatric neurology
About the author
Steven T. DeKosky is Professor of Neurology and Neuroscience and Deputy Director of the McKnight Brain Institute at the University of Florida, Gainesville, FL, USA, where he holds the Aerts-Cosper Professorship in Alzheimer Research. Before moving to the University of Florida, he was vice president and dean of the University of Virginia School of Medicine, and the James Carroll Flippin Professor of Medical Sciences. He was Professor and Chair of the Department of Neurology and Director of the Pitt/UPMC Alzheimer’s Disease Research Center, and served as a member of the American Board of Psychiatry and Neurology.Sanjay Asthana is Associate Dean for Gerontology and Professor and Head of the Division of Geriatrics & Gerontology at the UW-Madison School of Medicine and Public Health. He holds the Duncan G. and Lottie H. Ballantine endowed chair in geriatrics and serves as Director of both the Wisconsin Alzheimer’s Disease Research Center and the Geriatric Research, Education and Clinical Center at the William S. Middleton Memorial Veterans Hospital in Madison, Wisconsin. Prior to coming to UW, he served as a faculty at the University of Washington School of Medicine in Seattle, Washington.
