Pharmaceutical Perspectives of Nucleic Acid-Based Therapy

Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in vivo delivery of nucleic acids, the genesis of structure-synthesis-function interrelationships and the evolutionary approaches of these gene carriers. The book also addresses the influence of a viable gene expression system on disease by controlling gene regulation, transcription, translation and replication.

List of contents

Gene Expression. Modulation of Gene Expression. Biophysical Aspects of Nucleic Acids and Carriers. Intracellular Trafficking. Nucleic Acid Delivery Systems. Biodistribution and Pharmacokinetics. Clinical Applications of Gene Therapy.

About the author

Ram I. Mahato

Summary

Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in

Product details

• Assisted by: Sung Wan Kim (Editor), Sung Wan (University of Utah Kim (Editor), Kim Sung Wan (Editor), Ram I. Mahato (Editor), Ram I. (University of Tennessee Health Science Center Mahato (Editor), Mahato Ram I. (Editor)
• Publisher: Taylor and Francis
• Languages: English
• Product format: Hardback
• Released: 27.06.2002
• EAN: 9780415283854
• ISBN: 978-0-415-28385-4
• No. of pages: 560
• Weight: 1270 g
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Pharmacy; SCIENCE / Chemistry / General, MEDICAL / Pharmacology, Biology, life sciences, Pharmacology, Pharmaceutical technology, Pharmaceutical chemistry and technology