Molecular & Cellular Targets for Anti-Epileptic Drugs

A new phase of anti-epileptic drugs (AEDs) investigation has begun in which new drugs can be designed to target specific epileptogenic mechanisms. A rational approach to therapy today requires not only a full awareness of phamacokinetics of AEDs but also a thorough knowledge of their molecular targets and of their influence on excitatory and inhibitory mechanisms in the brain. This book provides a multi-author systematic look at this subject, from neurobiological bases to clinical applications. It includes four sections dealing with fundamental aspects of cortical excitability, models of epileptic disorders, targets for anti-epileptic drugs and rational approaches to therapy. Each chapter provides a review of a specific topic prepared by well known scientists active in the field, introducing their most recent results in a concise and comprehensive form.

Product details

• Assisted by: G Avanzini (Editor), G. Avanzini (Editor), M. Avoli (Editor), G Regesta (Editor), M Avoli (Editor), P Tanganelli (Editor), G. Regesta (Editor), P. Tanganelli (Editor)
• Publisher: John Libbey & Co
• Languages: English
• Product format: Paperback / Softback
• Released: 01.01.1997
• EAN: 9780861965540
• ISBN: 978-0-86196-554-0
• No. of pages: 266
• Dimensions: 180 mm x 249 mm x 20 mm
• Weight: 688 g
• Illustrations: Illustrations
• Series: Current Problems in Epilepsy; Current problems in epilepsy
• Subject: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine