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This book consists of invited reviews from a variety of experts in this area, integrating the present state of knowledge and exploring molecular, biochemical, neurophysiological, and behavioural approaches to studying nicotine and central nicotinic receptors. As well as having implications for health problems associated with tobacco use, the results have enhanced understanding of how central nicotinic mechanisms are involved in other psychiatric and neurological
states, such as Parkinson's Disease and Alzheimer's Disease.
List of contents
Jerome H. Jaffe: Tobacco, smoking, and nicotine dependence; Michael D.B. Swedburg, Jack E. Henningfield, & Steven R. Goldberg: Evidence of nicotine dependency from animal studies: self-administration, tolerance, and withdrawal; David M. Warburton: Psychopharmacological aspects of nicotine; Neal L. Benowitz, Herve Porchet, & Peyton Jacob: Pharmacokinetics, metabolism, and pharmacodynamics of nicotine; Paul B.S. Clarke: The central pharmacology of nicotine: electrophysiological approaches; Kjell Fuxe, Kurt Andersson, Anders Härfstrand, Peter Eneroth, Miguel Perez de la Mora, & Luigi F. Agnati: Effects of nicotine on synaptic transmission in the brain; S. Wonnacott: Characterization of nicotine receptor sites in the brain; I. P. Stolerman: Behavioural pharmacology of nicotine in animals; C. Reavill: Actions of nicotine on dopamine pathways and implications for Parkinson's disease; Kenneth J. Kellar & S. Wonnacott: Nicotinic-cholinergic receptors in Alzheimer's disease; M.A.H. Russell: Nicotine intake and its control over smoking; Index.
Summary
Nicotine in the form of tobacco has been more widely used by man than any other psychoactive drug. This is a collection of reviews by experts, on many aspects of the psychopharmacology of nicotine, integrating the present state of knowledge gained from a variety of different approaches.
Additional text
`This book is unique in providing a comprehensive and readable account of the state of knowledge......This book is particularly strong in the uniformly high quality of the contributions' Trends in Pharmacological Sciences