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As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.
Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from amyriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
List of contents
Risk Assessment for Breast Cancer.- Genetic Evaluation for Women at Increased Risk.- Imaging Screening and Surveillance.- Risk Reducing Surgery for BRCA1/2 Genetic Mutation Carriers.- Prophylactic Oophorectomy for Patients with Germline BRCA Mutations.- Pathology of BRCA Tumors.- Surgical Management of Breast Cancer in BRCA Mutation Carriers.- Medical Management of Breast Cancer in BRCA Mutation Carriers.- Radiation Oncology Considerations in the Management of Mutation Carriers with Breast Cancer.- Fertility Preservation in BRCA Carriers: Special Considerations.- Management of Male BRCA Mutation Carriers.- Psychosocial, Ethical, and Legal Implications for Mutation Carriers.
About the author
Anees B. Chagpar, MD, MSc, MPH, MA, MBA, FRCS(C), FACSAssociate Professor, Department of SurgeryDirector, The Breast Center -- Smilow Cancer Hospital at Yale-New HavenAssistant Director -- Global Oncology, Yale Comprehensive Cancer CenterYale University School of Medicine20 York Street, First floor Suite ANew Haven, CT 06510Phone: 203-200-1518
Summary
As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.
Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from amyriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
