Mycobacterial Lipid Antigens against Tuberculosis - Chemical synthesis and T Cell Activation

Tuberculosis (TB), caused by bacteria named Mycobacterium tuberculosis, is the second biggest infectious disease after AIDS. The cell envelope of M.tuberculosis contains many unique lipids which play a key role in the pathogenicity. Some of the lipids have been identified as antigens, the phenolic glycolipids (PGLs), the lipoarabinomannan (LAM), and the phosphatidylinositolmannoside (PIMs). This book provides a comprehensive discussion about the PIMs epitopes identification, synthesis, and its immunological activity presented by the the CD1 molecules.

About the author

Jin WANG nasceu na cidade de YiWu, província de ZheJiang, China, em 1985. Obteve o seu doutoramento em Microbiologia na Universidade de Toulouse III - Paul Sabatier, em França, em 2015, e é atualmente professor na Universidade de Professores de Yancheng. Os seus interesses de investigação são a química medicinal e a química supramolecular.

Product details

• Authors: Jin Wang
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 28.03.2017
• EAN: 9783330062580
• ISBN: 978-3-33-006258-0
• No. of pages: 204
• Subjects: Natural sciences, medicine, IT, technology > Chemistry; Non-fiction book > Nature, technology > Natural science