Read more
This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.
List of contents
J.M. Orth: Cell biology of testicular development in the fetus and neonate; P.N. Goodfellow et al: Molecular genetics of the human and mouse Y-chromosome; J.R. McCarrey: Development of the germ cell; C.E. Chubb: Genetic control of spermatogenesis and steroidogenesis; P.K. Donahoe: Mullerian inhibiting substance; C. Desjardins: Design and function of the microcirculation; L.L. Ewing: Leydig cell: structure/function; B.R. Zirkin: Regulation of spermatogenesis in the adult mammal: gonadotropins and androgens; C.W. Bardin, G.L. Gunsalus & C.Y. Cheng: The cell biology of the sertoli cell; D.M. Robertson, G.P. Risbridger & D.M. de Kretser: Inhibin and inhibin-related proteins; B.T. Hinton & T.T. Turner: The seminiferous tubular microenvironment; M.L. Meistrich & M.E.A.B. van Beek: Spermatogonial stem cells; H. Stern: The process of meiosis; Y. Clermont, R. Oko & L. Hermo: Cell biology of mammalian spermiogenesis; W.W. Wright: Cellular interactions in the seminiferous epithelium; N. Hecht: Gene expression during male germ cell development; D.J. Wolgemuth et al: Patterns of expression and potential functions of cellular oncogenes and heat shock protein genes during germ cell development; D.G. Myles: Sperm cell surface proteins of testicular origin: expression and localization in the testis and beyond; K.S.K. Tung: Regulation of autoimmune disease.
Summary
This book is on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes.
Additional text
490 pages of the highest quality text that will make this book a standard volume for years to come ... In short one of the best products that modern american authorship and academia can produce. Highly advised.
