Interactions between an anticancer agent and cyclodextrin - Inclusion complex formation and solution thermodynamics

Cyclodextrins have the ability to solubilize hydrophobic drugs by providing a conical cavity to encapsulate it and hence used for drug delivery. So it is interesting to study the interaction of an anti cancer agent i.e.; gallic acid with cyclodextrin in aqueous media. Different physico-chemical properties such as density, viscosity are used as tools to study the interactions. Uv-spectroscopic study establishes formaion of 1:1 inclusion complex. Various results reveal that the solutions are characterized predominantly by solute -solvent interactions and gallic acid behaves as a long-range structure maker.

About the author

Abhijit Sarkar is a researcher in the Department of Chemistry, University of North Bengal, West Bengal, India. His research areas include Solution Thermodynamics & Analytical Chemistry. He has published 14 research articles in different peer reviewed national & international journals.

Product details

• Authors: Abhiji Sarkar, Abhijit Sarkar, Biswajit Sinha
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 01.01.2017
• EAN: 9783330044425
• ISBN: 978-3-33-004442-5
• No. of pages: 56
• Subject: Natural sciences, medicine, IT, technology > Physics, astronomy > Thermodynamics