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Clear cell carcinoma (CCC) of the ovary with its unique clinical and biological features has attracted great attention, and calls for the publication of a specialized book on the subject. This is the first atlas that has narrowed its focus to CCC. Revealed here are the typical and variable histological features of CCC and related tumors. Hundreds of high-quality photographs help the reader to recognize the pathological features and clinical manifestations of CCC and to formulate diagnoses confidently and accurately. Data are based on the international central pathological review of the JGOG/GCIG3017 clinical trial in which experts around the world participated. Using a virtual slide system, interesting and significant features of CCC were discovered in the review of 652 cases. This book provides the newest information on the categorization and classification of CCC: growth patterns (papillary, tubocystic, solid, and adenofibromatous), cell types (classical hobnail and clear cell, eosinophilic, oxyphilic, and oncocytic), stromal changes (hyalinized, necrotic, hemorrhagic, lymphocytic infiltrative, luteinized, and psammomatous calcification), presence of endometriosis and atypical endometriosis, and borderline/atypical proliferative tumors. The Atlas of Clear Cell Carcinoma of the Ovary is an invaluable diagnostic resource for pathologists and gynecologic oncologists.
List of contents
Chapter 1 Introduction.- Chapter 2 Gross Pathology and Intraoperative Consultation.- Chapter 3 Typical Histopathology.- Chapter 4 Histopathologic Variations Chapter.- Chapter 5 Histopathologic Grading.- Chapter 6 Immunohistochemistry.- Chapter 7 Differential Diagnosis.
About the author
Junzo Kigawa, MD, PhD
Department of Gynecologic Oncology, Director of Tottori University Hospital Cancer Center
Tsunehisa Kaku, MD, PhD
Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University
Toru Sugiyama, MD, PhD
Obstetrics and Gynecology, Iwate Medical University School of Medicine
Steven G Silverberg
University of Maryland School of Medicine
Summary
Clear cell carcinoma (CCC) of the ovary with its unique clinical and biological features has attracted great attention, and calls for the publication of a specialized book on the subject. This is the first atlas that has narrowed its focus to CCC. Revealed here are the typical and variable histological features of CCC and related tumors. Hundreds of high-quality photographs help the reader to recognize the pathological features and clinical manifestations of CCC and to formulate diagnoses confidently and accurately. Data are based on the international central pathological review of the JGOG/GCIG3017 clinical trial in which experts around the world participated. Using a virtual slide system, interesting and significant features of CCC were discovered in the review of 652 cases. This book provides the newest information on the categorization and classification of CCC: growth patterns (papillary, tubocystic, solid, and adenofibromatous), cell types (classical hobnail and clear cell, eosinophilic, oxyphilic, and oncocytic), stromal changes (hyalinized, necrotic, hemorrhagic, lymphocytic infiltrative, luteinized, and psammomatous calcification), presence of endometriosis and atypical endometriosis, and borderline/atypical proliferative tumors. The Atlas of Clear Cell Carcinoma of the Ovary is an invaluable diagnostic resource for pathologists and gynecologic oncologists.
