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This book will present completely new, unique findings in eczema: sweat ducts that become occluded with staphylococcal biofilms trigger the innate immune system with TLR2 receptor activity and this leads to production of the "itching" and inflammation in this disease. Dermatologists and pediatricians treat eczema exceedingly well and this is ordinarily accomplished with corticosteroid containing topicals. However, after treatment, it is intriguing that aggressive moisturization and cautious bathing will in most instances prevent future flares of the disease, even though it is precipitated by bacteria and their biofilms. Diseases where eczema has been found with a completely unrelated disorder have shown occluded sweat ducts on histopathologic examination. These include Meyerson's nevus which has a nevus and eczema in the same biopsy and Doucas Kapetanakis-type of pigmented purpuric dermatosis that shows occluded sweat ducts along with the capillaritis.
List of contents
Clinical presentations.- Microbiology.- Pathology.- Immunology.- Genetics.- Physiology.- Treatment.- Diseases in which eczema is a secondary component (Meyerson's nevus and Doucas Kapetanakis pigmented purpuric dermatosis).- Diseases with occluded sweat ducts other than eczema (tinea pedis, axillary granular parakeratosis, seborrheic dermatitis).- The Story of Eczema in Pictures.- Epilogue: A comparison of psoriasis and eczema: both caused by bacteria, but neither an infection.
About the author
Dr. Allen is a graduate of Johns Hopkins University School of Medicine. He has served on the boards of the American Society of Dermatology and the American College of Physicians and has published over 40 scientific articles in the fields of dermatology and dermatopathology. For the past ten years, he has been the Professor and Chair of the Department of Dermatology of Drexel University College of Medicine. Dr. Herbert B. Allen’s specialties include dermatology and dermatopathology, skin pathology and fungal infections and is board-certified with the American Board of Dermatology and the American Board of Pathology.
Summary
This book will present completely new, unique findings in eczema: sweat ducts that become occluded with staphylococcal biofilms trigger the innate immune system with TLR2 receptor activity and this leads to production of the “itching” and inflammation in this disease. Dermatologists and pediatricians treat eczema exceedingly well and this is ordinarily accomplished with corticosteroid containing topicals. However, after treatment, it is intriguing that aggressive moisturization and cautious bathing will in most instances prevent future flares of the disease, even though it is precipitated by bacteria and their biofilms. Diseases where eczema has been found with a completely unrelated disorder have shown occluded sweat ducts on histopathologic examination. These include Meyerson’s nevus which has a nevus and eczema in the same biopsy and Doucas Kapetanakis-type of pigmented purpuric dermatosis that shows occluded sweat ducts along with the capillaritis.
Additional text
“The purpose is to present the biofilm bacterial
occlusion theory as the inciting inflammatory immune event leading to eczema.
The audience is all primary physicians and dermatologists.” (Patricia Wong,
Doody’s Book Reviews, November, 2015)
Report
"The purpose is to present the biofilm bacterial occlusion theory as the inciting inflammatory immune event leading to eczema. The audience is all primary physicians and dermatologists." (Patricia Wong, Doody's Book Reviews, November, 2015)
