High-Resolution Extreme Ultraviolet Microscopy - Imaging of Artificial and Biological Specimens with Laser-Driven Ultrafast XUV Sources

This thesis describes novel approaches and implementation of high-resolution microscopy in the extreme ultraviolet light regime. Using coherent ultrafast laser-generated short wavelength radiation for illuminating samples allows imaging beyond the resolution of visible-light microscopes. Michael Zürch gives a comprehensive overview of the fundamentals and techniques involved, starting from the laser-based frequency conversion scheme and its technical implementation as well as general considerations of diffraction-based imaging at nanoscopic spatial resolution. Experiments on digital in-line holography and coherent diffraction imaging of artificial and biologic specimens are demonstrated and discussed in this book. In the field of biologic imaging, a novel award-winning cell classification scheme and its first experimental application for identifying breast cancer cells are introduced. Finally, this book presents a newly developed technique of generating structured illumination by means of so-called optical vortex beams in the extreme ultraviolet regime and proposes its general usability for super-resolution imaging.

List of contents

Foreword.- Abstract.- Preamble.- Introduction and Fundamental Theory.- Experimental Setup.- Lensless Imaging Results.- Optical Vortices in the XUV.- Summary and Outlook.- Appendices.

Product details

• Authors: Michael Werner Zürch
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 01.01.2016
• EAN: 9783319385655
• ISBN: 978-3-31-938565-5
• No. of pages: 127
• Dimensions: 155 mm x 8 mm x 235 mm
• Weight: 236 g
• Illustrations: XVIII, 127 p. 44 illus., 30 illus. in color.
• Series: Springer Theses; Springer Theses
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Physical chemistry; B, Microscopy, Biology, life sciences, spectroscopy, Measurement, Spectroscopy and Microscopy, Testing of materials, Characterization and Analytical Technique, Materials science, Characterization and Evaluation of Materials, Physics and Astronomy, Scientific equipment, experiments & techniques, Medical physics, Biophysics, Scientific standards, measurement etc, Measurement Science and Instrumentation, Physical measurements, Biological physics, Biological and Medical Physics, Biophysics, Biological Microscopy, Bioanalysis and Bioimaging