Science of Synthesis. Vol.1 - Metal-Catalyzed Cyclization Reactions

Significant advances in metal-catalyzed reactions, especially cyclizations, have dramatically improved the efficiency of organic synthesis over the last three decades. To date these transformations are widely used in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: Metal-Catalyzed Cyclization Reactions" presents the most commonly used and significant metal-catalyzed reactions for modern organic synthesis. The basic principles, the current state of the art, scope, limitations, and mechanism of these reactions are also discussed. Typical examples of target synthesis are provided to help inspire further applications.

Volume 1 covers intramolecular coupling reactions (including Heck reactions), intramolecular allylations, and cyclopropane and cyclopropene ring openings. Also included are cyclization reactions of alkenes, alkynes, and allenes, cycloisomerizations, and intramolecular C-N and C-O bond formation.

About the author

Shengming Ma is Professor of Chemistry at the Department of Chemistry, East China Normal University and the Director of State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry (SIOC). After obtaining his Ph.D. from SIOC, he spent some time with Professors Venanzi (ETH Zurich, Switzerland) and Negishi (Purdue University, Indiana, USA) as a post-doctoral fellow and returned to China as a faculty member of SIOC in 1997.

Summary

Significant advances in metal-catalyzed reactions, especially cyclizations, have dramatically improved the efficiency of organic synthesis over the last three decades. To date these transformations are widely used in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: Metal-Catalyzed Cyclization Reactions" presents the most commonly used and significant metal-catalyzed reactions for modern organic synthesis. The basic principles, the current state of the art, scope, limitations, and mechanism of these reactions are also discussed. Typical examples of target synthesis are provided to help inspire further applications.
Volume 1 covers intramolecular coupling reactions (including Heck reactions), intramolecular allylations, and cyclopropane and cyclopropene ring openings. Also included are cyclization reactions of alkenes, alkynes, and allenes, cycloisomerizations, and intramolecular C-N and C-O bond formation.

Product details

• Assisted by: Shuanh Gao (Editor), Shuanhu Gao (Editor), Ma (Editor), Shengming Ma (Editor)
• Publisher: Thieme, Stuttgart
• Languages: English
• Product format: Paperback / Softback
• Released: 31.12.2016
• EAN: 9783131998712
• ISBN: 978-3-13-199871-2
• No. of pages: 566
• Dimensions: 170 mm x 255 mm x 33 mm
• Weight: 1132 g
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Organic chemistry; Chemie, Organische Chemie, ORGANIC CHEMISTRY REVIEW, ORGANIC METHOD, REFERENCE WORK, ORGANIC CHEMISTRY REACTIONS, CHEMISTRY OF ORGANIC COMPOUND, CHEMISTRY SYNTHETIC METHODS, SYNTHETIC METHODS, SYNTHETIC ORGANIC CHEMISTRY, ORGANIC REACTION, REVIEW ORGANIC SYNTHESIS, REVIEW SYNTHETIC METHODS, CHEMISTRY REFERENCE WORK, ORGANIC SYNTHESIS, ORGANIC CHEMISTRY SYNTHESIS, ORGANIC CHEMISTRY, ORGANIC SYNTHESES, Synthese, ORGANIC SYNTHESIS REFERENCE WORK, CHEMISCHE SYNTHESE, CHEMISTRY ORGANIC REACTION, ORGANISCH-CHEMISCHE SYNTHESE, SYNTHETIC TRANSFORMATION, CYCLIZATION, METAL CATALYSIS, METAL-CATALYZED REACTION