Read more
Crib death or sudden infant death syndrome is the most frequent death-causing syndrome during the first year of life, striking one infant in every 700-1,000. Despite a wide spectrum of theories and years of research, crib death remains a great enigma. This book describes systematic studies of the cardiovascular system and autonomic nervous system carried out in a large number of infants, newborns, and fetuses who have died suddenly and unexpectedly, as well as in age-matched control cases. The cardiovascular and neuropathological findings are presented in detail and the relationship between crib death and unexplained perinatal death is discussed. This monograph will aid pathologists, forensic pathologists, pediatricians, obstetricians and neonatologists in recognizing all potential morphological substrata. It puts forward a well-researched standardized postmortem protocol to be applied in all cases of sudden unexpected infant and perinatal death.
List of contents
INTRODUCTION.- Sudden Infant Death Syndrome (SIDS).- Sudden Intrauterine Unexplained Death (SIUD).- MATERIALS AND METHODS.- Clinical and pathological information form.- Post mortem regulation on SIDS.- Necropsy procedures.- Cardiac sampling and study of the conduction system.- Brainstem sampling and inherent techniques.- Study of the carotid bifurcation, ganglia and paraganglia.- Lung: evaluation of the development stage.- Immunohistochemistry and other techniques.- RESULTS.- Epidemiological results.- Cardiac Conduction findings.- Central autonomic nervous system findings.- Hypoplasia and agenesis of the arcuate nucleus.- Combined pulmonary and arcuate nucleus hypoplasia.- Peripheral autonomic nervous system findings.- DISCUSSION.- Cardiac conduction pathology.- Neuropathology.- CONCLUDING REMARKS.
Report
"This book covers sudden infant death syndrome (SIDS), sudden perinatal unexpected death (SPUD), and sudden intrauterine death (SIUD) from the standpoint of a pathologist. ... The audience includes pathologists, neonatologists, pediatricians and researchers, laboratory histotechnicians, pediatric nurses, medical students, general practitioners. ... the book also can be useful to obstetricians, emergency room physicians and nurses, cardiologists, neurologists, and neurosurgeons wishing to know more about this tragic entity. ... a good book for anyone with intellectual curiosity about this tragic entity." (Deepthi S. Rao, Doody's Book Reviews, May, 2015)
