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Pancreatitis: medical and surgical management provides gastroenterologists and GI surgeons, both fully qualified and in training, with a focused, evidence-based approach to the most exciting developments in the diagnosis and clinical management of pancreatitis.
Focusing mainly on the rapidly changing and innovative medical and surgical strategies to manage the disease, new surgical procedures such as endoscopic biliary intervention and minimally invasive necrosectomy to exciting new medical therapies like Antiprotease, Lexipafant, probiotics and enzyme treatment are all discussed.
Full colour throughout, with over 250 colour illustrations and with reference to the latest clinical guidelines from the AGA, ACG and UEGW at all times, it is an essential consultation tool for all those managing patients with this increasingly common condition.
List of contents
List of contributors, vii
1 Epidemiology and genetics of chronic pancreatitis, 1
2A Pathobiology of the acinar cell in acute pancreatitis, 10
2B Locoregional pathophysiology in acute pancreatitis: pancreas and intestine, 19
2C Pathophysiology of systemic inflammatory response syndrome and multiorgan dysfunction syndrome in acute pancreatitis, 29
3 Diagnosis, prediction, and classification, 38
4 Medical treatment, 47
5 Nutritional treatment in acute pancreatitis, 55
6 Gallstone pancreatitis: diagnosis and treatment, 64
7 Treatment of local complications, 75
8 Treatment of systemic complications and organ failure, 85
9 Specific treatment for acute pancreatitis, 91
10 Sequelae of acute pancreatitis, 101
11 History of chronic pancreatitis, 113
12A Epidemiology and pathophysiology: epidemiology and risk factors, 118
12B Epidemiology and pathophysiology: genetic insights into pathogenesis, 126
12C Pancreatic stellate cells: what do they tell us about chronic pancreatitis?, 143
12D Autoimmune pancreatitis: an update, 152
12E Etiology and pathophysiology: tropical pancreatitis, 161
12F Mechanisms and pathways of pain in chronic pancreatitis, 169
13A Imaging of chronic pancreatitis, 179
13B Endoscopic ultrasonography in chronic pancreatitis, 188
14A Pancreatic enzyme replacement therapy (PERT), 195
14B Nutritional treatment: antioxidant treatment, 205
14C Pancreatogenic diabetes: etiology, implications, and management, 211
14D Nutrition without a pancreas: how does the gut do it?, 225
15A Endoscopic management of chronic pancreatitis, 233
15B Shocking and fragmenting pancreatic ductal stones, 245
15C Endoscopic management: celiac plexus blockade, 249
16A A brief history of modern surgery for chronic pancreatitis, 256
16B Surgery for chronic pancreatitis: indications and timing of surgery, 261
16C Chronic pancreatitis: surgical strategy in complicated diseases, 265
16D Surgery for chronic pancreatitis: pancreatic duct drainage procedures, 273
16E Surgical management: resection and drainage procedures, 279
16F The role of pancreatoduodenectomy in the management of chronic pancreatitis, 286
17A Total pancreatectomy and islet cell autotransplantation: patient selection, 295
17B Total pancreatectomy and islet cell autotransplantation: the science of islet cell preservation, from pancreas to liver, 299
17C Total pancreatectomy and islet cell autotransplantation: long-term assessment of graft function, 308
Index, 321
About the author
David B. Adams, M.D. is Professor and Chief of Gastrointestinal and Laparoscopic Surgery and Co-Director of the Digestive Disease Center at the Medical University of South Carolina, Charleston, South Carolina. He is the author of over 100 manuscripts and book chapters which deal with his academic and clinical research interests in chronic pancreatitis.
Peter B. Cotton, M.D. is a British Gastroenterologist best known for his advancement in digestive disease, pioneering and naming the ERCP procedure and creating the Digestive Disease Center at the Medical University of South Carolina where he is Professor of Medicine. He has been active in National and International organizations, and has given invited lectures and demonstrations in more than 50 countries His bibliography includes over 900 medical publications, including more than 300 original contributions in peer reviewed journals, and 10 books.
Nicholas J. Zyromski, M.D. is Associate Professor of Surgery at Indiana University. He served as an NIH research fellow at the Mayo Clinic in Rochester, Minnesota, and is currently the Indiana University HPB Surgery Fellowship Program Director. Dr. Zyromski's principal clinical interest is in pancreatic disease; his basic and translational research interest focuses on the inflammatory response of acute pancreatitis as well as the influence of obesity and adipose tissue on pancreatic diseases - pancreatic cancer and acute pancreatitis.
John Windsor, M.D. holds a personal chair in surgery at the University of New Zealand, Auckland. He is Director of Surgical Research, Director of Surgical Research Network , Co-Director of Applied Surgery and Metabolism Laboratory and Surgical Centre for Outcomes Research and Evaluation, Principle Investigator Pancreas Research Group, and Associate Investigator Maurice Wilkins Centre of Biodiscovery. His primary research is in the pathophysiology and clinical management of acute and chronic pancreatitis. He is Associate Editor of the journal
Pancreatology and the
World Journal of Surgery.
Summary
Pancreatitis: medical and surgical management provides gastroenterologists and GI surgeons, both fully qualified and in training, with a focused, evidence-based approach to the most exciting developments in the diagnosis and clinical management of pancreatitis.
Report
"Overall, this is an excellent book on all aspects of acute and chronic pancreatitis. It is concise yet comprehensive, written by well-known and well-published, credible authorities. It will be useful not just to the intended audience of gastroenterologists and GI surgeons, but also to all physicians involved in the care of patients with pancreatitis. Most books try to cover all aspects of this complex condition in a summary fashion, which is not possible. This book fills in the gaps by providing a focused, comprehensive review including latest evidence and guidelines. 5 Stars!" (Doody Enterprises July 2017)
