Read more
Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules.
* Aids researchers developing polymers and materials for biomedical applications
* Describes biopolymers from a synthetic perspective, which other similar books do not do
* Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification
List of contents
List of Contributors
Part I. Pseudo-Peptides, Polyamino acids and Polyoxazolines
Chapter 1 - Characterization of Polypeptides and Polypeptoides -Methods and Challenges
David Huesmann and Matthias Barz
Chapter 2- Poly(2-Oxazoline): The structurally Diverse Biocompatibilizing Polymer
Rodolphe Obeid
Chapter 3- Poly(2-oxazoline) Polymers - synthesis, characterization and Applications in Development of Therapeutics
Randall W. Moreadith and Tacey X. Viegas
Chapter 4- Polypeptoid Polymers: Synthesis, Characterization and Properties
Brandon A. Chan, Sunting Xuan, Ang Li, Jessica M. Simpson and Donghui Zhang
Part II - Advanced Polycondensates
Chapter 5 - Polyanhydrides: Synthesis and Characterization
Rohan Ghadi, Eameema Muntimadugu Wahid Khan and Abraham J. Domb
Chapter 6 - New Routes to Tailor-Made Polyesters
Kazuki Fukushima and Tomoko Fujiwara
Chapter 7 - Polyphosphoesters: An old biopolymer in a new light
Kristin N. Bauer, Hisaschi T.C. Tee, Evandro M. Alexandrino and Frederik R. Wurm
Part III. Cationically Charged Macromolecules
Chapter 8 - Design and Synthesis of Amphiphilic Vinyl Copolymers with Antimicrobial Activity
Leanna L. Foster, Masato Mizutani, Yukari Oda, Edmund F. Palermo and Kenichi Kuroda
Chapter 9 - Enhanced Polyethylenimine-Based Delivery of Nucleic Acids
Jeff Sparks, Tooba Anwer and Khursheed Anwer
Chapter 10 - Cationic graft copolymers for DNA engineering
Atsushi Maruyama and Naohiko Shimada
Part IV. Biorelated polymers by Controlled Radical Polymerization
Chapter 11 - Synthesis of (Bio)degradable Polymers by Controlled/"Living" Radical Polymerization"
Shannon R. Woodruff and Nicolay V. Tsarevsky
Part V. Polydrugs and Polyprodrugs
Chapter 12 - Polymerized drugs - a novel approach to controlled release systems
B. Demirdirek, J. J. Faig, R. Guliyev and K.E.Uhrich
Chapter 13 - Structural design and synthesis of polymer prodrugs
Petr Chytil, Libor Kostka and Tomás Etrych
Part VI. Biocompatibilization of Surfaces
Chapter 14 - Polymeric ultrathin films for surface modifications
Henning Menzel
Chapter 15 - Surface Functionalization of Biomaterials by Poly(2-oxazoline)s
Giulia Morgese and Edmondo M. Benetti
Chapter 16 - Biorelated polymer brushes by surface initiated reversible deactivation radical polymerization
Rueben Pfukwa, Lebohang Hlalele and Bert Klumperman
Part VII. Self-assembled Structures and Formulations
Chapter 17 - Synthesis of amphiphilic invertible polymers for biomedical applications
A.M. Kohut, I.O. Hevus, S.A. Voronov and A.S. Voronov
Chapter 18 - Bioadhesive Polymers for Drug Delivery
Eenko Larrañeta and Ryan F. Donnelly
INDEX
About the author
CARMEN SCHOLZ, PhD, is a Professor in the Department of Chemistry at the University of Alabama in Huntsville, where her research concentrates on the synthesis and characterization of biocompatible and biodegradable polymers. She serves on the editorial boards of 3 journals (including Wiley's
Polymer International), has published over 70 papers or proceedings, and edited 5 books.
Summary
Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and shows their application in biomedicine. An added emphasis deals with characterizing these polymers through structure verification.
