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This volume presents classical approaches to in vivo neuropharmacology and neurophysiology, such as c-fos, electrochemistry, microdialysis microstimulation, and push-up superfusion. It also explores exciting new methods for behavioral analysis, and techniques based on optogenetics and non-invasive magnetic resonance imaging. The chapters of this book cover topics such as principles of stereotaxy, pharmaco-based fMRI and neurophysiology in humans and non-human primates, electrical nerve stimulation and central microstimulation, involvement of neurotransmitters in mnemonic processes, the impact of cannabinoids on motor activity, as well as the involvement of nitric oxide in neurotoxicity produced by psychostimulant drugs. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.
Cutting-edge andpractical, In Vivo Neuropharmacology and Neurophysiology is a valuable resource for experienced and less experienced investigators of brain function and brain disorders.
List of contents
Principles of Stereotaxy in Small Animals.- EEG Indices of Cortical Network Formation and their Relevance for Studying Variance in Subjective Experience and Behavior.- Pharmaco-Based fMRI and Neurophysiology in Non-Human Primates.- Optogenetic Manipulations of Neuronal Network Oscillations: Combination of Optogenetics and Electrophysiological Recordings in Behaving Mice.- 3D-Video-Based Computerized Behavioral Analysis for In Vivo Neuropharmacology and Neurophysiology in Rodents.- Operant Self-Administration of Chocolate in Rats: An Addiction-Like Behavior.- Electrical Nerve Stimulation and Central Microstimulation.- In Vivo Biosensor Based on Prussian Blue for Brain Chemistry Monitoring: Methodological Review and Biological Applications.- Monitoring Extracellular Molecules in Neuroscience by In Vivo Electrochemistry: Methodological Considerations and Biological Applications.- Push-Pull Superfusion: A Technique forInvestigating Involvement of Neurotransmitters in Brain Function.- Involvement of Neurotransmitters in Mnemonic Processes, Response to Noxious Stimuli and Conditioned Fear: A Push-Pull Superfusion Study.- Neurophysiological Approaches for In Vivo Neuropharmacology.- Involvement of Neurotransmitters in Behavior and Blood Pressure Control.- Functional Mapping of Somatostatin Receptors in Brain: In Vivo Microdialysis Studies.- The Impact of Cannabinoids on Motor Activity and Neurochemical Correlates.- Modeling Schizophrenia: Focus on Developmental Models.- Immunohistochemical Analysis of Fos Protein Expression for Exploring Brain Regions Related to Central Nervous System Disorders and Drug Actions.- Involvement of Nitric Oxide in Neurotoxicity Produced by Psychostimulant Drugs.
Summary
This volume presents classical approaches to in vivo neuropharmacology and neurophysiology, such as c-fos, electrochemistry, microdialysis microstimulation, and push-up superfusion. It also explores exciting new methods for behavioral analysis, and techniques based on optogenetics and non-invasive magnetic resonance imaging. The chapters of this book cover topics such as principles of stereotaxy, pharmaco-based fMRI and neurophysiology in humans and non-human primates, electrical nerve stimulation and central microstimulation, involvement of neurotransmitters in mnemonic processes, the impact of cannabinoids on motor activity, as well as the involvement of nitric oxide in neurotoxicity produced by psychostimulant drugs. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.
Cutting-edge andpractical, In Vivo Neuropharmacology and Neurophysiology is a valuable resource for experienced and less experienced investigators of brain function and brain disorders.
