Metal Chelation in Medicine

Klappentext Metal chelators are emerging as versatile tools with many medical applications. Chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body, removing them from intracellular or extracellular spaces. In addition, metal chelators can be applied as imaging agents in various forms of clinical scanning techniques. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field, this book covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques. Zusammenfassung This book describes the role of chelating agents in managing metal intoxications and storage diseases and is directed at clinicians. Inhaltsverzeichnis Metal toxicity - essential elements/non-essential elements; Non-invasive assessment of brain iron overload; Chelators for imaging; Basic principles of metal chelation and chelation design; Synthetic strategies for therapeutic chelators; Therapeutic applications of chelation therapy; Treatment of systemic iron overload; Treatment of neurodegenerative diseases by chelators; Chelation of actinides, plutonium, uranium

Product details

• Authors: Prof. Robert (Catholique University of L Crichton, Robert (Catholique University of Louvain Crichton, Robert R (Catholique University of Louva Crichton, Robert R Ward Crichton, Robert R. Crichton, Robert R. Ward Crichton
• Assisted by: Robert Crichton (Editor), Robert R Crichton (Editor), Robert R (Catholique University of Louvain Crichton (Editor), Robert R. Crichton (Editor), Robert Hider (Editor), Robert C Hider (Editor), Robert C (King's College London Hider (Editor), Robert C. Hider (Editor), Roberta J Ward (Editor), Roberta J (Catholique University of Louvain Ward (Editor), Roberta J. Ward (Editor)
• Publisher: Royal Society Of Chemistry
• Languages: English
• Product format: Hardback
• Released: 31.10.2016
• EAN: 9781782620648
• ISBN: 978-1-78262-064-8
• No. of pages: 322
• Series: Metallobiology; Metallobiology
• Subject: Natural sciences, medicine, IT, technology > Chemistry > Inorganic chemistry