T-cell Receptor Gamma Gene Rearrangement in T-cell Neoplasm - Detection Using Genescan

The discrimination between reactive and malignant cell populations in some patients with suspected T-cell lymphoproliferative disorders can be complicated and less straightforward. Often, the dilemma lies in determining whether a population of lymphocytes is reactive or neoplastic. In such cases, T-cell receptor (TCR)gene clonality studies have proved useful as an additional diagnostic tool. The TCRGamma gene is a preferred target for TCR gene clonality as it is rearranged at an early stage of T lymphoid development, rearranged in a large percent of T-cell neoplasms, and also because of its relative structural simplicity.

About the author

Eman A. Soliman, M.Sc, studied at faculty of Science at Mansoura University. Works as a medical analysis specialist in Oncology center at Mansoura University. Expert in molecular biology fields including PCR, Genescan and Sequencing techniques.

Product details

• Authors: Eman Adel
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 01.01.2016
• EAN: 9783659859090
• ISBN: 978-3-659-85909-0
• No. of pages: 176
• Subject: Natural sciences, medicine, IT, technology > Biology > Genetics, genetic engineering