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This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.
List of contents
Continuous Flow Synthesis - a Short Perspective.- Equipment Overview.- Organic Synthesis in Dedicated Continuous Flow Systems - Transition Metal Catalyzed Carbon-Carbon and Carbon-Heteroatom Bond Forming Reactions.- Organic Synthesis in Dedicated Continuous Flow Systems - Rearrangement Reactions.- Organic Synthesis in Dedicated Continuous Flow Systems - Cycloaddition Reactions.- Organic Synthesis in Dedicated Continuous Flow Systems - Reductions and Oxidations.- Organic Synthesis in Dedicated Continuous Flow Systems - Heterocyclic and Multi-Step Syntheses.- Organic Synthesis in Dedicated Continuous Flow Systems - Synthesis of Radiolabeled Compounds.- Organic Synthesis in Dedicated Continuous Flow Systems - Enzymatic Reactions.- Organic Synthesis in Dedicated Continuous Flow Systems - Further Chemistry Examples.- Outlook.
About the author
Toma Glasnov is currently holding an Assistant Professor position and is the head of the Christian Doppler Laboratory for Flow Chemistry at the Institute of Chemistry (KFU-Graz). His research is devoted on the application of continuous-flow processing in the area of organic synthesis focusing on hazardous reactions, high-temperature/pressure syntheses as well as photochemical reactions, multicomponent synthesis and synthesis of biologically active molecules and molecular sensors.
Summary
This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.
