IMMUNE TOLERANCE

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews how self-tolerant T- and B-cell populations are produced. The contributors discuss the elimination of autoreactive lymphocytes during their development in the thymus and bone marrow, the suppression of autoreactive cells by regulatory T cells in the periphery, and intrinsic mechanisms that produce clonal anergy. The roles of dendritic cells in antigen presentation and mechanisms that prevent autoreactivity in natural killer cells are also covered.

Product details

• Authors: Diane J Mathis, Diane J. Mathis, Alexander Y Rudensky
• Assisted by: Diane Mathis (Editor), Diane J Mathis (Editor), Diane J (Harvard Medical School) Mathis (Editor), Diane J. Mathis (Editor), Alexander Rudensky (Editor), Alexander Y Rudensky (Editor), Alexander Y (Howard Hughes Medical Institute and Memorial Sloan-Kettering Cancer Center) Rudensky (Editor), Alexander Y. Rudensky (Editor)
• Publisher: Cold Spring Harbor Laboratory Press,U.S.
• Languages: English
• Product format: Hardback
• Released: 30.06.2013
• EAN: 9780879698959
• ISBN: 978-0-87969-895-9
• No. of pages: 168
• Dimensions: 183 mm x 263 mm x 16 mm
• Weight: 554 g
• Series: Cold Spring Harbor Perspective; Cold Spring Harbor Perspectives in Biology; Cold Spring Harbor Perspectives in Biology; Cold Spring Harbor Perspective
• Subject: Natural sciences, medicine, IT, technology > Biology > General, dictionaries