Fast Oscillations in Cortical Circuits

The study of cortical oscillations is of great interest to those working in many areas of neuroscience. A fast coherent EEG rhythm called gamma or "40 Hz" has been implicated in cognition, as it may play a role in binding together features of objects. This rhythm may also be important for consciousness, as a number of drugs that induce general anesthesia disrupt the synchronization of the rhythm at clinically relevant concentrations. There is also suggestive evidence implicating dysfunction of gamma rhythms in Alzheimer's disease, and perhaps in other neuropsychiatric disorders.

Summary

Using a combination of electrophysiological and computer modelling techniques, this book analyzes how large networks of neurons can produce both epileptic seizures and functionally relevant synchronized oscillations. Topics covered include single hippocampal pyramid cells and synaptic interactions.

Product details

• Authors: John G R Jefferys, John G. R. Jefferys, John G. R. (Professor of Neuroscience Jefferys, John G. R. (Professor of Neuroscience) Jefferys, Roger D Traub, Roger D. Traub, Roger D. (SUNY Downstate Medical Center) Traub, Miles A Whittington, Miles A. Whittington, Miles A. (Newcastle University) Whittington
• Assisted by: Tomaso A. (Professor Poggio (Editor), Terrence J. (Francis Crick Professor Sejnowski (Editor)
• Publisher: Penguin Random House LLC
• Languages: English
• Product format: Hardback
• Released: 24.05.1999
• EAN: 9780262201186
• ISBN: 978-0-262-20118-6
• No. of pages: 308
• Dimensions: 158 mm x 235 mm x 26 mm
• Weight: 685 g
• Series: Computational Neuroscience; Computational Neuroscience series; Fast Oscillations in Cortical Circuits; Computational Neuroscience Series; Computational Neuroscience
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine