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This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.
Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.
List of contents
Animal Models of Traumatic Brain Injury.- Experimental Radiosurgery in Animal Models.- Stereotactic Surgery in Rats.- Rat Middle Cerebral Artery (MCA) Occlusion Models Which Involve a Frontotemporal Craniectomy.- Inferior Colliculus Approach in a Rat.- Why Robots Entered Neurosurgery.- Impact Model of Spinal Cord Injury.- Acute Clip Contusion Compression Model of SCI.- Microsurgical Approach to Spinal Canal in Rats.- Stereotaxic Injection into the Rat Spinal Cord.- Surgical Access to Cisterna Magna Using Concorde-Like Position for Cell Transplantation in Mice and CNS Dissection within Intact Dura for Evaluation of Cell Distribution.- Animal Models for Experimental Neurosurgery of Peripheral and Cranial Nerves.- Surgery of the Brain and Spinal Cord in a Porcine Model.- Real-Time Convection Delivery of Therapeutics to the Primate Brain.- Focal Cerebral Ischemia by Permanent Middle Cerebral Artery Occlusion in Sheep - Surgical Technique, Clinical Imaging, and Histopathological Results.- A Non-Human Primate Model of Delayed Cerebral Vasospasm after Aneurismal Subarachnoid Hemorrhage.
Summary
This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.
Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.
Additional text
“This is an excellent sourcebook reference with respect to animal models of stroke, trauma, and neurodegenerative diseases. Rat models of Huntingtons, Parkinson’s, and epilepsy are discussed well. Sites for neurotoxin injections are diagrammed in a step by step approach. … A step by step approach is covered for each model introduced. This is a good book atlas for technicians, students, and research scientists.” (Joseph J. Grenier, Amazon.com, June, 2016)
Report
"This is an excellent sourcebook reference with respect to animal models of stroke, trauma, and neurodegenerative diseases. Rat models of Huntingtons, Parkinson's, and epilepsy are discussed well. Sites for neurotoxin injections are diagrammed in a step by step approach. ... A step by step approach is covered for each model introduced. This is a good book atlas for technicians, students, and research scientists." (Joseph J. Grenier, Amazon.com, June, 2016)
