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This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
List of contents
Introduction.- Metallothioneins: structure and functions.- Metallothionein-3.- The role of metallothioneins in carciogenesis.- Metallothioneins and immune function.
Summary
This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
Additional text
“This is a concise monograph on the pathophysiological role of molecules called metallothioneins in cancerous cells including GI, GU, renal, endocrine, and CNS systems. Normal physiology of these compounds is described well. The biochemical pathways, signal transduction, and cellular mechanisms are discussed in depth. … I recommend this book to those interested in physiology and cancer research. Students, fellows and experts will all find this reference beneficial.” (Joseph J. Grenier, Amazon.com, June, 2016)
Report
"This is a concise monograph on the pathophysiological role of molecules called metallothioneins in cancerous cells including GI, GU, renal, endocrine, and CNS systems. Normal physiology of these compounds is described well. The biochemical pathways, signal transduction, and cellular mechanisms are discussed in depth. ... I recommend this book to those interested in physiology and cancer research. Students, fellows and experts will all find this reference beneficial." (Joseph J. Grenier, Amazon.com, June, 2016)
