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Informationen zum Autor Alfred A. Bartolucci is Professor Emeritus in the Department of Biostatistics, School of Public Health, University of Alabama at Birmingham. He has over 300 peer-reviewed publications (manuscripts and book chapters) in the areas of original statistical methodologic research and clinical and laboratory statistical applications. An endowed scholarship in Biostatistics at UAB was established in his honor. Karan P. Singh is currently Professor of Medicine and serves as Director of the Biostatistics and Bioinformatics Shared Facility at the University of Alabama at Birmingham Comprehensive Cancer Center. He has authored or coauthored over 250 peer-reviewed articles, book chapters, and peer-reviewed congress or conference proceedings. He is a Fellow of the American Statistical association. Sejong Bae is Professor of Medicine and serves as Co-Director of the Biostatistics and Bioinformatics Shared Facility; Deputy Director of the Coronary Artery Risk Development in Young Adults Coordination Center; and Director of Data, Information, and Statistics Core in the Division of Preventive Medicine. In 2009, he was elected to International Statistical Institute. Klappentext Introduction to Statistical Analysis of Laboratory Data presents a detailed discussion of important statistical concepts and methods of data presentation and analysis* Provides detailed discussions on statistical applications including a comprehensive package of statistical tools that are specific to the laboratory experiment process* Introduces terminology used in many applications such as the interpretation of assay design and validation as well as "fit for purpose" procedures including real world examples* Includes a rigorous review of statistical quality control procedures in laboratory methodologies and influences on capabilities* Presents methodologies used in the areas such as method comparison procedures, limit and bias detection, outlier analysis and detecting sources of variation* Analysis of robustness and ruggedness including multivariate influences on response are introduced to account for controllable/uncontrollable laboratory conditions Zusammenfassung Introduction to Statistical Analysis of Laboratory Data presents a detailed discussion of important statistical concepts and methods of data presentation and analysis* Provides detailed discussions on statistical applications including a comprehensive package of statistical tools that are specific to the laboratory experiment process* Introduces terminology used in many applications such as the interpretation of assay design and validation as well as "fit for purpose" procedures including real world examples* Includes a rigorous review of statistical quality control procedures in laboratory methodologies and influences on capabilities* Presents methodologies used in the areas such as method comparison procedures! limit and bias detection! outlier analysis and detecting sources of variation* Analysis of robustness and ruggedness including multivariate influences on response are introduced to account for controllable/uncontrollable laboratory conditions Inhaltsverzeichnis Preface xi Acknowledgments xv 1 Descriptive Statistics 1 1.1 Measures of Central Tendency 1 1.2 Measures of Variation 4 1.3 Laboratory Example 7 1.4 Putting it All Together 8 1.5 Summary 10 References 10 2 Distributions and Hypothesis Testing in Formal Statistical Laboratory Procedures 11 2.1 Introduction 11 2.2 Confidence Intervals (CT) 19 2.2.1 Confidence Interval (CI) for the Population Mean - The t -Distribution 20 2.2.2 Confidence Interval for the Variance and Standard Deviation 21 2.3 Inferential Statistics - Hypothesis Testing 23 2.3.1 t -Test for Means 25 2.3.2 Test for Variation: Coef...
