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Comprehension of the theories of aging requires rudimentary knowledge of oxidation and reduction reactions, protein function, cell organelles, mitosis, acquired immunity, and evolution, among other basic biological concepts. Without these fundamentals, students of biological aging struggle to learn the essentials of biological aging and how to appreciate the research advances in the field.
Human Biological Aging: From Macromolecules To Organ-Systems is an introduction to human aging from the level of macromolecules to organ systems. Age changes in proteins, DNA, polysaccharides and lipids are discussed relative to known age-related alterations in structure and function produced by free radicals and oxidants. At the cellular level, age-dependent mechanisms that diminish organelle function are described. Cellular phenomena of replicative senescence apoptosis, autophagy and neuroplasticity are detailed as to their contribution to compromised cellular functions. Authored by a leader in the field, Human Biological Aging: From Macromolecules To Organ-Systems is an invaluable introduction for those studying human aging.
List of contents
Section 1 The foundation
Chapter 1 Orientation
Chapter 2 Measurements and models
Chapter 3 Evolutionary theory of aging
Section 2 Basic components
Chapter 4 Aging of macromolecules
Chapter 5 Aging of cells
Section 3 Organ-systems: outer covering & Movement
Chapter 6 Aging of the skin
Chapter 7 Aging of the skeletal muscle system
Chapter 8 Aging of the skeletal system
Section 4 Internal organ-systems: cardiovascular, pulmonary, gastrointestinal & Urinary
Chapter 9 Aging of the cardiovascular system
Chapter 10 Aging of the pulmonary system
Chapter 11 Aging of the gastrointestinal and urinary systems
Section 5 Regulatory organ-systems: central nervous system, sensory, endocrine & immune systems
Chapter 12 Aging of the central nervous system
Chapter 13 Aging in the sensory system
Chapter 14 Aging of the endocrine system
Chapter 15 Aging of the immune system
About the author
Glenda E. Bilder is an Instructor at Gwynedd Mercy College in Gwynedd Valley, PA, USA.
Summary
Comprehension of the theories of aging requires rudimentary knowledge of oxidation and reduction reactions, protein function, cell organelles, mitosis, acquired immunity, and evolution, among other basic biological concepts.
