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Klappentext THE authoritative guide for clinical laboratory immunologyFor over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. The Manual features detailed descriptions of general and specific methodologies, placing special focus on the interpretation of laboratory findings, and covers the immunology of infectious diseases, including specific pathogens, as well as the full range of autoimmune and immunodeficiency diseases, cancer, and transplantation.Written to guide the laboratory director, the Manual will also appeal to other laboratory scientists, especially those working in clinical immunology laboratories, and pathologists. It is also a useful reference for physicians, mid-level providers, medical students, and allied health students with an interest in the role that immunology plays in the clinical laboratory. Zusammenfassung THE authoritative guide for clinical laboratory immunologyFor over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses! the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. The Manual features detailed descriptions of general and specific methodologies! placing special focus on the interpretation of laboratory findings! and covers the immunology of infectious diseases! including specific pathogens! as well as the full range of autoimmune and immunodeficiency diseases! cancer! and transplantation.Written to guide the laboratory director! the Manual will also appeal to other laboratory scientists! especially those working in clinical immunology laboratories! and pathologists. It is also a useful reference for physicians! mid-level providers! medical students! and allied health students with an interest in the role that immunology plays in the clinical laboratory. Inhaltsverzeichnis Editorial Board xi Contributors xiii Foreword: How it Began xxiii Preface xxv Author and Editor Conflicts of Interest xxvii Section A General Methods 1 Volume Editor: Robert G. Hamilton Section Editor: Thomas A. Fleisher 1 Introduction 3 Thomas A. Fleisher 2 Molecular Methods for Diagnosis of Genetic Diseases Involving the Immune System 5 Amy P. Hsu 3 The Human Microbiome and Clinical Immunology 19 Frederic D. Bushman 4 Protein Analysis in the Clinical Immunology Laboratory 26 Roshini Sarah Abraham and David R. Barnidge Section B Immunoglobulin Methods =/ 47 Volume Editor: Robert G. Hamilton Section Editor: David F. Keren 5 Introduction 49 David F. Keren 6 Immunoglobulin Genes 51 Thomas J. Kipps, Emanuela M. Ghia, and Laura Z. Rassenti 7 Immunoglobulin Quantification and Viscosity Measurement 65 Jeffrey S. Warren 8 Clinical Indications and Applications of Serum and Urine Protein Electrophoresis 74 David F. Keren and Richard L. Humphrey 9 Immunochemical Characterization of Immunoglobulins in Serum, Urine, and Cerebrospinal Fluid 89 Elizabeth Sykes and Yvonne Posey 10 Cryoglobulins, Cryofibrinogenemia, and Pyroglobulins 101 ...