Locus and gene analyses in five inherited disorders - Genetic studies and statistical tools to analyze five inherited disorders in consanguineous families

Genetic analyses in five inherited disorders In this study, computer based parametric tests including two and multi point analysis and simulation were applied to evaluate the linkage information obtained by autozygosity mapping from five rare autosomal recessive disorders: multiple joint stiffness (MJS), mental retardation associated with hypertension (MR-HT), hyaline body myopathy (HBM), ataxia-telangiectasia with microcephaly (AT- MCPH) and Seckel syndrome. The borders of gene loci for these disorders were thus better drawn.

About the author

Sibel A. Ugur Iseri, PhD: Studied Molecular Biology and Genetics at Bogazici University, Istanbul

Product details

• Authors: Sibel Ugur Iseri
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 01.01.2010
• EAN: 9783838346076
• ISBN: 978-3-8383-4607-6
• No. of pages: 108
• Subject: Natural sciences, medicine, IT, technology > Biology > Genetics, genetic engineering