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This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist.The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.
List of contents
ForewordSTRUCTURE: FOLDAMER DESIGN CONCEPTSFoldamers Based on Local Conformation PreferencesFoldamers Based on Remote Intrastrand InteractionsFoldamers Based on Solvophobic EffectsFoldamer Hybrids: Defined Supramolecular Structures from Flexible MoleculesControl of Polypeptide Chain Folding and AssemblySimulation of Folding EquilibriaFUNCTION: FROM PROPERTIES TO APPLICATIONSFoldamer-based Molecular RecognitionBiological Application of FoldamersProtein DesignNucleic Acid Foldamers: Design, Engineering and Selection of Programmable Biomaterials with Recognition, Catalytic and Self-assembly PropertiesHelically Folding PolymersPolyisocyanides: Stiffened FoldamersFoldamers at Interfaces
About the author
Stefan Hecht obtained his doctorate under the guidance of Prof. Jean M. J. Fréchet at the University of California. After becoming a research investigator at Berlin, he is now group leader at the Max-Planck-Institut für Kohlenforschung. He has been a fellow of the Studienstiftung des Deutschen Volkes and has received both the Sofja Kovalevskaja Award of the Alexander von Humboldt Foundation as well as the MIT Technology Review Top 100 Young Innovator Award.
Ivan Huc received his PhD in 1994 from the Université of Paris VI, jointly supervided by Dr. C. Rolando (Ecole Normale Supérieure) and Prof. J. Rebek Jr. (MIT). After a post-doctoral period with Dr. J.-P. Behr in Illkirch, he received a CNRS researcher position in Nobel Prize winner Prof. J.-M. Lehn's laboratories in Strasbourg, where he stayed until 1998. Since then, he has been a group leader at the Institut Européen de Chimie et Biologie (Bordeaux) where he holds a research director position.
Summary
This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist.
The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.
Report
"...sollte somit sowohl äußerst wertvolle Anregungen für Forschende als auch wichtige Aspekte für Forschende als auch wichtige Aspekte für moderne Vorlesungen über Polymersynthese liefern."Nachrichten aus der Chemie1/2008"Jeder, der auf diesem Gebiet forschen oder sich einen Überblick über den aktuellen Forschungsstand verschaffen will, wird sich glücklich schätzen, das Buch zur Hand zu haben."Angewandte Chemie2008-120/4
