Nanomaterials for the Life Sciences - 6: Semiconductor Nanomaterials

Informationen zum Autor Challa Kumar is currently the Director of Nanofabrication & Nanomaterials at the Center for Advanced Microstructures and Devicees (CAMD)! Baton Rouge! USA. He is also the President and CEO of Magnano Technologies! a company established to commercialize nanomaterials for applications in life sciences. His research interests are in developing novel synthetic methods! including those based on microfluidic reactors! for multifunctional nanomaterials. He has also been involved in the development of innovative therapeutic & diagnostic tools based on nanotechnology. He has eight years of industrial R&D experience working for Imperial Chemical Industries and United Breweries. He is the founding Editor-in-Chief of the Journal of Biomedical Nanotechnology! published by American Scientific Publishers and Series editor for the ten-volume book series! Nanotechnologies for the Life Sciences (NtLS)! published by Wiley-VCH. Klappentext The SeriesThe new book series "Nanomaterials for the Life Sciences"! successor to the highly acclaimed series "Nanotechnology for the Life Sciences"! provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals! synthesis and characterization strategies! structure-property relationships and biomedical applications. The new series brings nanomaterials to the life scientists and life science to the materials scientists so that synergies are seen and developed to the fullest.Written by international experts of various facets of this exciting field of research! the ten volumes of this single source of information comprehensively cover the complete range of nanomaterials for medical! biological and cybernetic applications. The series is aimed at scientists of the following disciplines: biology! chemistry! materials science! physics! bioengineering! and medicine! together with cell biology! biomedical engineering! pharmaceutical chemistry! and toxicology! both in academia and fundamental research as well as in pharmaceutical companies.Volume 6: Semiconductor NanomaterialsThis volume is divided in three parts: Imaging and Diagnostics! Therapy and Synthesis! Characterization and Toxicology. Quantum dots and their application to medicine are discussed throughout the book.For more information on NmLS! please visitwww.NmLS.wiley-vch.de Zusammenfassung 'Semiconductor Nanomaterials' is divided in three parts: Imaging and Diagnostics! Therapy and Synthesis! Characterization and Toxicology. Quantum dots and their application to medicine are discussed throughout the book. Inhaltsverzeichnis PART I: Imaging and DiagnosticsQUANTUM DOTS FOR CANCER IMAGINGIntroductionCancerQuantum Dots: Physics and ChemistryIn Vitro Screening and Detection of Cancer Biomarkers Using MicroarraysQuantum Dot Cytotoxicity and Potential Safety ConcernsConcluding Remarks and Future PerspectivesQUANTUM DOTS FOR TARGETED TUMOR IMAGINGIntroductonTypes of Quantum Dots (QDs)Surface Modifications of QDs for BioapplicationsMethods of Delivering QDs into TumorsRecent Advances in QDs TechnologyConclusion and PerspectivesMULTIPLEXED BIOIMAGING USING QUANTUM DOTSIntroductionThe Need for Novel Multiplex Imaging SystemsQuantum DotsBioimaging Applications of Quantum DotsTranslation to Clinical Biomarker MeasurementSummary and Future PerspectivesMULTIPLEXED DETECTION USING QUANTUM DOTSIntroductionIn Vitro Multiplexed Analysis Using QDsMultiplexed Imaging Using QDsSummaryPART II: TherapyMEDICAL DIAGNOSTICS OF QUANTUM DOT-BASED PROTEIN MICRO- AND NANOARRAYSIntroductionProtein ArraysFrom Microarrays to Nanoarrays: Why Nanoarrays?Functionalization of QDs for Attachment to Proteins or Other BiomoleculesFabrication of Protein BiochipsQDs Probes in Clinical ApplicationsQDs-Labeled Protein NanoarraysSummary and Future PerspectivesIMAG...

List of contents

PART I: Imaging and DiagnosticsQUANTUM DOTS FOR CANCER IMAGINGIntroductionCancerQuantum Dots: Physics and ChemistryIn Vitro Screening and Detection of Cancer Biomarkers Using MicroarraysQuantum Dot Cytotoxicity and Potential Safety ConcernsConcluding Remarks and Future PerspectivesQUANTUM DOTS FOR TARGETED TUMOR IMAGINGIntroductonTypes of Quantum Dots (QDs)Surface Modifications of QDs for BioapplicationsMethods of Delivering QDs into TumorsRecent Advances in QDs TechnologyConclusion and PerspectivesMULTIPLEXED BIOIMAGING USING QUANTUM DOTSIntroductionThe Need for Novel Multiplex Imaging SystemsQuantum DotsBioimaging Applications of Quantum DotsTranslation to Clinical Biomarker MeasurementSummary and Future PerspectivesMULTIPLEXED DETECTION USING QUANTUM DOTSIntroductionIn Vitro Multiplexed Analysis Using QDsMultiplexed Imaging Using QDsSummaryPART II: TherapyMEDICAL DIAGNOSTICS OF QUANTUM DOT-BASED PROTEIN MICRO- AND NANOARRAYSIntroductionProtein ArraysFrom Microarrays to Nanoarrays: Why Nanoarrays?Functionalization of QDs for Attachment to Proteins or Other BiomoleculesFabrication of Protein BiochipsQDs Probes in Clinical ApplicationsQDs-Labeled Protein NanoarraysSummary and Future PerspectivesIMAGING AND TRACKING OF VIRUSES USING QUANTUM DOTSIntroductionQuantum Dot-Biomolecule HybridsQuantum Dots for Single Virus Tracking in Living CellsQuantum Dots for the Sensitive Detection of Virus and InfectionConclusionsNANOMATERIALS FOR RADIATION THERAPYIntroductionA Brief Introduction to Radiation Therapy, and its LimitationsPhysical RadiosensitizersRadiation Therapy in Combination with Photodynamic Therapy Using Semiconductor Nanoparticles as the Energy MediatorNanobrachytherapyNanoparticles as RadioprotectorsRadiation Dosimeters Using Semiconductor NanomaterialsConclusionsPROSPECTS OF SEMICONDUCTOR QUANTUM DOTS FOR IMAGING AND PHOTODYNAMIC THERAPY OF CANCERIntroductionBasic Principles and Challenges in PDTAdvantages of Quantum Dots for PDTSynthesis of Quantum DotsOptical Properties of Quantum DotsPreparation of Biocompatible Quantum DotsNontargeted Intracellular Delivery QDsTargeting Cancer Cells with QDsQuantum Dots for Photodynamic Therapy of CancerToxicity of QDsConclusionsPART III: Synthesis, Characterization, and ToxicologyTYPE-I AND TYPE-II CORE-SHELL QUANTUM DOTS: SYNTHESIS AND CHARACTERIZATIONIntroductionCore-Shell UV-Vis Nanoparticulate MaterialsCharacterization of NanoheterostructuresCore-Shell Infrared Nanoparticulate MaterialsType I Core-Shell Infrared StructuresType II Core-Shell Infrared StructuresSummary and ConclusionsNANOWIRE QUANTUM DOTSIntroductionQuantum DotsGrowth of Quantum Dots, Nanowires and Nanowire HeterostructuresApplications for Nanowires and Nanowire Quantum DotsConclusionsQUANTUM DOT-CORE SILICA GLASS-SHELL NANOMATERIALS: SYNTHESIS, CHARACTERIZATION, AND POTENTIAL BIOMEDICAL APPLICATIONSIntroductionHistorical OverviewIncorporation of Quantum Dots in Glass Beads for BioapplicationsPreparation of Cadmium-Free Quantum Dots With Water DispersibilitySummary and Future PerspectiveTOXICOLOGY AND BIOSAFETY EVALUATIONS OF QUANTUM DOTSIntroductionThe Physico-Chemical Properties of Quantum DotsToxicity and Role of Oxidative StressADME and Biosafety EvaluationThe Mitochondrion as a Prime Target for QD ToxicityEnvironmental and Ecological ConcernsConcluding Comments and Future Perspectives

Product details

• Authors: Challa S. S. R. Kumar
• Assisted by: Challa S. S. R. Kumar (Editor), Chall S S R Kumar (Editor)
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 31.03.2015
• EAN: 9783527321667
• ISBN: 978-3-527-32166-7
• No. of pages: 498
• Sets: Nanomaterials for the Life Sciences; Nanomaterials for the Life Sciences
• Subject: Natural sciences, medicine, IT, technology > Chemistry > Miscellaneous