Read more
While many books cover solid phase synthesis and combinatorial synthesis, this one is unique in its exclusive coverage of the other aspects of solid-phase synthesis. As such, it contains everything you need to know -- from supported reagents, to scavengers, resins, and the synthesis of biomolecules and natural products.An invaluable companion for all chemists and biochemists working in university research and industry.
List of contents
INTRODUCTIONThe (Classic Concept of) Solid SupportMolecularly Imprinted PolymersNanoparticles Functionalized with Bioactive Molecules: Biomedical ApplicationsSOLID-SUPPORTED REAGENTS AND SCAVENGERSOxidizing and Reducing ReagentsBase and Acid ReagentsNucleophilic, Electrophilic, and Radical ReactionsCoupling and Introducing Building Block ReagentsSupported/Tagged Scavengers for Facilitating High-Throughput ChemistryMetal ScavengersRESIN-BOUND CATALYSTSPolymer-Supported OrganocatalystsTransition Metal CatalystsChiral Auxiliaries on Solid SupportImmobilized Enyzmes in Organic SynthesisRESINS FOR SOLID-PHASE SYNTHESISAcid-Labile ResinsBase/Nucleophile-Labile ResinsSafety-Catch and Traceless Linkers/Resins in SPOSPhotolabile and Miscellaneous Linkers/ResinsSOLID-PHASE SYNTHESIS OF BIOMOLECULES. THE STATE OF THE ART (FROM THE RESIN POINT OF VIEW)PeptidesOligonucleotides and their DerivativesOligosacharidesHigh Throughput Synthesis of Natural Products
About the author
Judit Tulla-Puche is a senior scientist at the Institute for Research in Biomedicine in the group of Professor Fernando Albericio. She received her Ph.D. in chemistry at the University of Minnesota under the supervision of Professor George Barany, and then moved to the Barcelona Science Park. Her research efforts are directed at the synthesis of cyclic peptides and depsipeptides with anticancer activity, and the development of drug delivery methodologies.
Fernando Albericio is the Executive Director of the Barcelona Science Park, Professor at the University of Barcelona, and group leader at the Institute for Research in Biomedicine. His major research interests cover practically all aspects of peptide synthesis and combinatorial chemistry methodologies, as well as synthesis of peptides and small molecules with therapeutic activities. He has published over 500 papers and is currently editor of Amino Acids and the International Journal of Peptide Research and Therapeutics.
Summary
While many books cover solid phase synthesis and combinatorial synthesis, this one is unique in its exclusive coverage of the other aspects of solid-phase synthesis. As such, it contains everything you need to know -- from supported reagents, to scavengers, resins, and the synthesis of biomolecules and natural products.
An invaluable companion for all chemists and biochemists working in university research and industry.
Report
"The editors have succeeded in providing an authoritative summary of the use of functional resins in organic synthesis. The book impresses by the enormous range of topics that are discussed. Every chemistry library in academia or industry should own a copy of this book." ( Angewandte Chemie , May 2009)
