Temperature-Programmed Gas Chromatography

This book provides a comprehensive up-to-date overview of temperature-programmed gas chromatography (GC). The first part of the book introduces the reader to the basics concepts of GC, as well as the key properties of GC columns. The second part describes the mathematical and physical background of GC. In the third part, different aspects in the formation of a chromatogram are discussed, including retention times, peak spacing and peak widths.An invaluable reference for any chromatographer and analytical chemist, it provides all the answers to questions like:* At what temperature does a solute elute in a temperature-programmed analysis?* What is the value of the retention factor of eluting solute?* How wide are the peaks?* How large is the time distance between two peaks?* How do all these parameters depend on the heating rate?

List of contents

PrefacePART I: IntroductionBASIC CONCEPTS AND TERMSA COLUMNRetention MechanismsStructuresOperational ModesSpecific and General Properties of a ColumnBoundariesPART II: BackgroundLINEAR SYSTEMSProblem Review: Metrics for Peak Retention Time and WidthChromatograph as an Information Processing SystemProperties of Linear SystemsMathematical Moments of FunctionsProperties of Mathematical MomentsPulsesMIGRATION OF A SOLID OBJECTVelocity of an ObjectParameters of Migration PathRelations between Path Parameters and Object ParametersSOLUTE-LIQUID INTERACTION IN GAS CHROMATOGRAPHYDistribution Constant and Retention FactorChromatographic Parameters of Solute-Liquid InteractionAlternative Expressions of Ideal Retention ModelLinearized Retention ModelRelations between Characteristic ParametersMOLECULAR PROPERTIES OF IDEAL GASTheoryGas Viscosity and Related Parameters - Empirical FormulaeEmpirical Formulae for Solute Diffusity in a GasFLOW OF IDEAL GASMass-Conserving FlowPneumatic ParametersRelations Between Pneumatic ParametersPART III: Formation of ChromatogramFORMATION OF RETENTION TIMESSolute MobilitySolute-Column Interaction and Solute MigrationGeneral Equations of a Solute Migration and ElutionUniform Solute Mobility in Isobaric AnalysisScalability of Retention Times in Isobaric AnalysesDimensionless ParametersBoundaries of Linearized ModelFORMATION OF PEAK SPACINGStatic GC AnalysisClosely Migrating Solutes in Dynamic AnalysisIsobaric Linear Heating Ramp and Highly Interactive SolutesProperties of Generic SolutesFORMATION OF PEAK WIDTHSOverviewLocal Plate HeightSolute Zone in Non-Uniform MediumApparent Plate Number and HeightThin Film ColumnsThick Film ColumnsTemperature-Programmed AnalysesTemperature-Programmed Thin Film ColumnsPacked ColumnsScalability of Peak Widths in Isobaric AnalysesPlate Height: Evolution of the ConceptIncorrect Plate Height Theory

About the author

Leonid M. Blumberg obtained his academic degrees in electrical engineering and training in mathematics from leading institutions of higher education in St. Petersburg, Russia. In 1977, he immigrated to USA and joined Hewlett-Packard Co. as an electrical engineer. Later he became a resident theoretician responsible for optimization of GC instrumentation and analytical methods. In this capacity, he participated in defining several new GC instruments. After leaving HP in 1998, Dr. Blumberg founded a consulting company, Fast GC Consulting, and continued the development of theoretical foundation for optimization of conventional, fast and multi-dimensional GC where he is a world leading expert.Leonid Blumberg authored 50 scientific publications and patented 19 inventions.

Summary

This book provides a comprehensive up-to-date overview of temperature-programmed gas chromatography (GC). The first part of the book introduces the reader to the basics concepts of GC, as well as the key properties of GC columns. The second part describes the mathematical and physical background of GC. In the third part, different aspects in the formation of a chromatogram are discussed, including retention times, peak spacing and peak widths.

An invaluable reference for any chromatographer and analytical chemist, it provides all the answers to questions like:

* At what temperature does a solute elute in a temperature-programmed analysis?
* What is the value of the retention factor of eluting solute?
* How wide are the peaks?
* How large is the time distance between two peaks?
* How do all these parameters depend on the heating rate?

Report

"It best serves as a reference book on GC theory and, at that, it probably is the best one out there. I expect I will continue to use this book for many, many years to come and I recommend it to anyone using GC for anything more than the simplest of purposes." ( Journal of Chemical Education , 18 November 2012)

Product details

• Authors: Leonid M Blumberg, Leonid M. Blumberg
• Publisher: Wiley-VCH
• Languages: English
• Product format: Hardback
• Released: 31.03.2015
• EAN: 9783527326426
• ISBN: 978-3-527-32642-6
• No. of pages: 340
• Dimensions: 180 mm x 249 mm x 24 mm
• Weight: 898 g
• Illustrations: 86 SW-Abb., 32 Tabellen
• Subjects: Natural sciences, medicine, IT, technology > Chemistry; Chromatographie