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This first book on this fascinating topic is edited by one of today's most famous and internationally respected organic chemists, renowned for his pioneering synthesis of the cyclopropenyl cation.For his part, Ronald Breslow has brought together leading scientists in this expanding area to provide a novel overview of protein-, cyclodextrin-, metal- and porphyrin-based artificial enzymes as well as enzyme-like polymers and dendrimers.A must for all scientists interested in this emerging field.
List of contents
Introduction to Artificial Enzymes (R. Breslow)Vitamin B6 Enzyme Models (L. Liu and R. Breslow)Evolution of Synthetic Polymers with Enzyme-like Catalytic Activities (I. Klotz and J. Suh)Mimicking Enzymes with Antibodies (D. Hilvert)Protein-based Artificial Enzymes (B. Duckworth and M. Distefano)Artificial Hydrolytic Metalloenzymes (J. Chin and H. Kim)Artificial Restriction Enzymes - Tools for Future Molecular Biology and Biotechnology (Y. Yamamoto and M. Komiyama)
About the author
Ronald Breslow is Professor of Chemistry at Columbia University. In addition to his work on Artificial Enzymes and Biomimetic Chemistry he has created novel aromatic and antiaromatic molecules, and a new approach to cancer therapy that is in advanced clinical trials. His numerous awards include the U. S. National Medal of Science. He is a member of the U.S. National Academy of Science, and an honorary member of the Royal Society (Britain), the Royal Society of Chemistry, the Chemical Societies of Japan and Korea, and the Indian Academy of Science.
Summary
This first book on this fascinating topic is edited by one of today's most famous and internationally respected organic chemists, renowned for his pioneering synthesis of the cyclopropenyl cation.
For his part, Ronald Breslow has brought together leading scientists in this expanding area to provide a novel overview of protein-, cyclodextrin-, metal- and porphyrin-based artificial enzymes as well as enzyme-like polymers and dendrimers.
A must for all scientists interested in this emerging field.
Report
"Das Buch ist eine gelungene Ergänzung der Literatur über synthetische Enzyme..." Angewandte Chemie"... sehr wertvoll für Chemiker und Biochemiker, die sich mit den Mechanismen enzymatischer Katalyse beschäftigen. ... Alle Beiträge dieses Buches sind von Experten geschrieben und geben nach einer guten Einführung in die Problematik sehr detaillierte Informationen und, vor allen Dingen, zahlreiche Literaturzitate ..., die es dem Leser erlauben, noch tiefer in die Materie einzutauchen. ...ein sehr gutes Nachschlagewerk und gibt durch die Fülle an Details eine gute Übersicht über dieses interessante Forschungsgebiet." Chemie Ingenieur Technik"...empfehlenswerte Buch vermittelt einen guten, allgemeinen Überblick über ein faszinierendes und sehr facettenreiches Forschungsgebiet, in dem es noch viele offene Fragen zu klären gilt."Nachrichten aus der Chemie
