Beneficial of Medical Plant to overcoming Bacterial Resistance - Antibacterial Activity of Ethanolic Extract of Ocimum basilicum Leaves Against Diarrhea Caused by E. coli in Rats

The present study was carried out to investigate the antibacterial activity of Ocimum basilicum ethanolic extract in-vitro and in-vivo by inducing diarrhea in rat which was caused by oral administration of pathogenic Escherichea coli. From the results obtained, it could be concluded that ethanolic extract of O.B leaves at dose 200 mg/kg. BW. was more effective and safe in comparison with antibacterial agent and other O.B dose, this anti-diarrheal activity of O.B ethanolic extract may be due to its constituents of secondary metabolites alkaloids like (hyoscyamine and scopolamine), phenols like (Catechol and pyrogallol), tannins, saponins, flavonoids like (Quercetin and Epicatechin), steroids and terpenoids, that are responsible for the antibacterial activity with different mechanisms of action.

About the author

Sarhan Rashid Sarhan-was born in July 1981 in Alkut, Iraq.His Academic Status is Assist. Lecturer,Qualification: MSc. In Vet. Pharmacology and Toxicology, Place of work: College of Veterinary Medicine and Surgery/Wasit University. Wasit, Iraq.Last Current Position is Pharmacology Department Decision.Currently he is a PhD student.

Product details

• Authors: Orooba M S Ibrahem, Orooba M. S. Ibrahem, Orooba M.S. Ibrahem, Sarha Rashid, Sarhan Rashid
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 01.01.2015
• EAN: 9783659648083
• ISBN: 978-3-659-64808-3
• No. of pages: 104
• Subject: Natural sciences, medicine, IT, technology > Medicine > Veterinary medicine